# Manusights > Pre-submission scientific manuscript review service. AI diagnostic ($29, 30 minutes) or expert human review by researchers published in Nature, Cell, and Science ($1,000-$1,800, 3-7 days). For a complete list of every page on the site, see [Full Site Index](https://manusights.com/llms-full.txt). Manusights helps researchers improve manuscripts before journal submission. The site focuses on pre-submission review, journal-calibrated feedback, acceptance-rate and review-time guidance, and practical publishing resources for biomedical and adjacent research fields. Every expert reviewer has first-author publications in Cell, Nature, or Science. The AI diagnostic verifies citations against CrossRef and PubMed, flags manuscript risks, and calibrates feedback to the target journal. ## Core Products - [AI Manuscript Diagnostic](https://manusights.com/ai-review): Upload a PDF, choose a target journal, get a manuscript readiness score with top risks, citation verification, and journal fit analysis. - [Expert Human Review](https://manusights.com/services): Expert manuscript review by researchers with first-author publications in Nature, Cell, and Science. NDA-protected with journal-calibrated feedback. - [Sample AI Report PDF](https://manusights.com/downloads/manusights-sample-ai-report.pdf): Example output of the AI diagnostic showing report structure, scoring, and revision recommendations. - [Sample Expert Review PDF](https://manusights.com/downloads/manusights-sample-review.pdf): Example expert review showing feedback depth, specificity, and revision guidance. ## Specialized Services - [Avoid Desk Rejection](https://manusights.com/services/avoid-desk-rejection): Pre-submission screening for scope mismatches, formatting issues, and editorial triage risks. - [Manuscript Revision Help](https://manusights.com/services/manuscript-revision-help): Structured revision support after reviewer comments or a revise-and-resubmit decision. - [Respond to Reviewers](https://manusights.com/services/respond-to-reviewers): Point-by-point reviewer response strategy, drafting help, and rebuttal structure. - [For Authors](https://manusights.com/for-authors): Overview of Manusights services for individual researchers and PIs. ## Journal Guides Comprehensive journal-specific guides covering impact factors, acceptance rates, scope, editorial preferences, common rejection reasons, and submission strategy. Full directory at [All Journal Guides](https://manusights.com/journals). ### Top Biomedical Journals - [Nature](https://manusights.com/journals/nature): Submission strategy, scope, acceptance rate, and editorial preferences for Nature. - [Science](https://manusights.com/journals/science): How to submit to Science, what editors look for, and common rejection patterns. - [Cell](https://manusights.com/journals/cell): Cell submission guide covering scope, review process, and what distinguishes accepted papers. - [Lancet](https://manusights.com/journals/lancet): Lancet submission strategy, clinical trial expectations, and editorial standards. - [NEJM](https://manusights.com/journals/nejm): New England Journal of Medicine guide covering clinical manuscript requirements and selectivity. - [JAMA](https://manusights.com/journals/jama): JAMA submission strategy, manuscript types, and structured abstract requirements. - [BMJ](https://manusights.com/journals/bmj): BMJ editorial preferences, open peer review process, and scope. - [Nature Medicine](https://manusights.com/journals/nature-medicine): How Nature Medicine differs from Nature and what translational papers get through. - [Nature Biotechnology](https://manusights.com/journals/nature-biotechnology): Technology-driven life science research, methods papers, and commercial relevance requirements. ### Specialty Journals - [Circulation](https://manusights.com/journals/circulation): Premier cardiology journal covering clinical and basic science submissions. - [Gut](https://manusights.com/journals/gut): Leading gastroenterology journal with guidance on scope, timelines, and editorial priorities. - [Blood](https://manusights.com/journals/blood): Hematology flagship with manuscript categories, review process, and acceptance patterns. - [Immunity](https://manusights.com/journals/immunity): High-impact immunology journal and how it differs from Nature Immunology. - [Neuron](https://manusights.com/journals/neuron): Premier neuroscience journal with scope boundaries, editorial preferences, and common rejection reasons. - [Cancer Cell](https://manusights.com/journals/cancer-cell): Top cancer biology journal with mechanistic depth expectations and translational framing. - [Cell Metabolism](https://manusights.com/journals/cell-metabolism): Cell Press metabolism journal with scope, editorial standards, and submission strategy. - [Lancet Oncology](https://manusights.com/journals/lancet-oncology): Clinical oncology trials, real-world evidence standards, and Lancet-family review process. - [Gastroenterology](https://manusights.com/journals/gastroenterology): AGA flagship journal with GI research scope and standards. - [European Heart Journal](https://manusights.com/journals/european-heart-journal): ESC flagship cardiology journal and regional editorial differences authors should know. ### High-Volume Open Access - [Nature Communications](https://manusights.com/journals/nature-communications): Nature portfolio open-access journal with scope, APC context, and transfer patterns. - [PNAS](https://manusights.com/journals/pnas): PNAS submission paths, direct vs contributed routes, and multidisciplinary scope. - [PLOS ONE](https://manusights.com/journals/plos-one): Large open-access journal using technical-soundness review rather than novelty review. - [eLife](https://manusights.com/journals/elife): Open-access journal with public reviews, editorial-model changes, and submission strategy. - [Scientific Reports](https://manusights.com/journals/scientific-reports): Nature portfolio broad-scope journal and how it differs from Nature Communications. - [Science Advances](https://manusights.com/journals/science-advances): AAAS open-access journal with scope differences from Science and review expectations. ## Acceptance Rates - [Journal Acceptance Rates Directory](https://manusights.com/acceptance-rates): Acceptance-rate data across 129 covered journals, sortable by field and impact factor. ## Journal Comparisons - [All Journal Comparisons](https://manusights.com/journals/compare): Side-by-side analyses across 21 submission decisions and competing journals. - [Nature vs Science](https://manusights.com/journals/compare/nature-vs-science): Nature vs Science compared: impact factors, acceptance rates, editorial philosophy, word limits, and a decision framework for choosing between them. - [NEJM vs Lancet vs JAMA vs BMJ](https://manusights.com/journals/compare/medical-journals-compared): NEJM vs Lancet vs JAMA vs BMJ compared. Impact factors, acceptance rates, editorial priorities, and a decision framework for clinical researchers. - [Cell Press Journals: How to Choose](https://manusights.com/journals/compare/cell-press-family): Cell Press journal guide: Cell, Cancer Cell, Immunity, Cell Metabolism, Molecular Cell, Neuron, Cell Reports. Hierarchy, transfers, and how to choose. - [Nature Family: Choosing the Right Journal](https://manusights.com/journals/compare/nature-family): Nature family journal guide: Nature through Nature Communications. The hierarchy, transfer cascade, and how to choose the right one. - [Immunity vs Nature Immunology](https://manusights.com/journals/compare/immunity-vs-nature-immunology): Immunity vs Nature Immunology compared: editorial models, impact factors, review speed, and a decision framework for immunologists. - [Nature Communications vs Scientific Reports](https://manusights.com/journals/compare/nature-communications-vs-scientific-reports): Nature Communications vs Scientific Reports compared: impact factor, editorial bar, novelty expectations, reviewer mindset, and where technically strong ## Resources for Researchers - [Pre-Submission Checklist](https://manusights.com/resources/pre-submission-checklist): 25-point manuscript readiness checklist before journal submission. - [Impact Factor Explained](https://manusights.com/resources/impact-factor-explained): How Journal Impact Factor works and how to use it in journal selection. - [Journal Metrics Guide](https://manusights.com/resources/journal-metrics-guide): CiteScore, SJR, SNIP, h-index, and other publishing metrics explained. - [Cover Letter Guide](https://manusights.com/resources/cover-letter-guide): How to write a cover letter that clarifies novelty, fit, and editorial relevance. - [Open Access Guide](https://manusights.com/resources/open-access-guide): Gold, Green, and Diamond OA models, APCs, and compliance basics. - [Peer Review Explained](https://manusights.com/resources/peer-review-explained): Editorial screening, external review, revisions, and final decisions explained. - [Peer Review Timelines](https://manusights.com/resources/peer-review-timelines): Expected review durations across major journals and what drives delays. - [Systematic Reviews Guide](https://manusights.com/resources/systematic-reviews): PRISMA-aligned guidance for systematic reviews and meta-analyses. - [AI Tools for Researchers](https://manusights.com/resources/ai-tools-for-researchers): Responsible use of AI in manuscript preparation and journal policy context. - [Predatory Journals Guide](https://manusights.com/resources/predatory-journals-biomedical): How to identify and avoid predatory publishers in biomedical research. - [Scientific CV Guide](https://manusights.com/resources/scientific-cv-guide): Academic CV strategy for jobs, grants, and fellowship applications. - [Preprint Guide](https://manusights.com/resources/preprint-guide): How and when to post preprints on bioRxiv, medRxiv, and similar servers. - [Reporting Guidelines](https://manusights.com/resources/reporting-guidelines): CONSORT, PRISMA, STROBE, ARRIVE, and other reporting frameworks. - [Responding to Reviewers](https://manusights.com/resources/responding-to-reviewers): A practical guide to rebuttal letters and point-by-point responses. - [Author Rights Guide](https://manusights.com/resources/author-rights-guide): Copyright transfer, licensing, and retaining reuse rights. - [Data Sharing Requirements](https://manusights.com/resources/data-sharing-requirements): Journal and funder expectations for datasets, repositories, and sharing statements. - [Journal Submission Specs](https://manusights.com/resources/journal-submission-specs): Formatting requirements, word limits, figure specs, and reference styles. - [Biomedical Journal Acceptance Rates](https://manusights.com/resources/biomedical-journal-acceptance-rates): Acceptance-rate benchmarks across biomedical journals and disciplines. - [NIH F31 Guide](https://manusights.com/resources/nih-f31-guide): Predoctoral fellowship strategy, eligibility, and application advice. - [NIH F32 Guide](https://manusights.com/resources/nih-f32-guide): Postdoctoral fellowship strategy and application guidance. - [NIH K99 Guide](https://manusights.com/resources/nih-k99-guide): Pathway to Independence Award strategy and planning. - [NSF GRFP Guide](https://manusights.com/resources/nsf-grfp-guide): Graduate Research Fellowship Program application strategy. - [How to Write a Peer Review](https://manusights.com/resources/how-to-peer-review): A practical guide to reviewing manuscripts for journals. - [Research Statement Guide](https://manusights.com/resources/research-statement-guide): How to write an academic research statement for applications. - [Statistical Resources Guide](https://manusights.com/resources/statistical-resources-guide): Core statistics references and resources for biomedical researchers. - [Reference Library](https://manusights.com/resources/reference-library): Reference hub for publishing, review, and journal-selection materials. ## Blog Research-backed articles on journal selection, manuscript preparation, peer review strategy, publication ethics, and review workflows. - [All Blog Posts](https://manusights.com/blog): Full searchable archive across 826 published articles. - [Journal Guides](https://manusights.com/blog?category=Journal+Guides): 524 articles on specific journal strategies, impact factors, and submission processes. - [Publishing Strategy](https://manusights.com/blog?category=Publishing+Strategy): 150 articles on journal selection, avoiding desk rejection, and publication planning. - [Product Comparisons](https://manusights.com/blog?category=Product+Comparisons): 31 articles comparing manuscript preparation services and tools. - [Journal Comparisons](https://manusights.com/blog?category=Journal+Comparisons): 44 side-by-side journal analyses for common submission decisions. - [Manuscript Preparation](https://manusights.com/blog?category=Manuscript+Preparation): 22 articles on writing, structuring, and polishing manuscripts. - [Peer Review](https://manusights.com/blog?category=Peer+Review): 11 articles on navigating peer review, revisions, and reviewer responses. ### Key Blog Posts - [What to Do After Desk Rejection: Your Recovery Roadmap](https://manusights.com/blog/what-to-do-after-desk-rejection): Step-by-step recovery guide for desk-rejected manuscripts. - [10 Desk Rejection Red Flags Editors Spot in 60 Seconds](https://manusights.com/blog/desk-rejection-red-flags): Common reasons editors reject without external review. - [Desk Rejection: What It Means, Why It Happens, and What to Do Next](https://manusights.com/blog/desk-rejection-reasons): How desk rejections happen and how to improve your next submission. - [How to Choose the Right Journal for Your Paper (A Practical Guide)](https://manusights.com/blog/how-to-choose-journal-for-paper): Practical framework for selecting the right journal for your paper. - [How to Respond to Reviewer Comments (Without Losing Your Mind)](https://manusights.com/blog/respond-reviewer-comments): How to answer reviewer comments without weakening your position. - [Journal Cover Letter Template: 5 Filled-In Examples for Any Journal (2026)](https://manusights.com/blog/cover-letter-journal-submission): Templates and examples for journal submission cover letters. - [10 Signs Your Paper Isn't Ready to Submit (Yet)](https://manusights.com/blog/signs-paper-not-ready-submit): Self-assessment checklist before submitting to any journal. - [AI-Generated Peer Reviews: How Common Are They and What Researchers Can Do](https://manusights.com/blog/ai-reviewing-your-paper): What AI manuscript review can and cannot do before submission. ## For Institutions & Publishers - [For Libraries](https://manusights.com/for-libraries): How research libraries can offer Manusights as a support service. - [For Journals](https://manusights.com/for-journals): Partnership opportunities for editors and publishers. - [For Institutions](https://manusights.com/for-institutions): Institutional licensing, pricing, and admin-focused overview. ## Lead Magnet - [25-Point Pre-Submission Audit Checklist](https://manusights.com/checklist): Free downloadable PDF checklist covering formatting, methodology, statistics, references, and journal-specific requirements. ## Trust & Company - [About Manusights](https://manusights.com/about): Company background, mission, and publishing-quality positioning. - [Trust & Security](https://manusights.com/trust): Confidentiality, data handling, and NDA-related safeguards. - [Contact](https://manusights.com/contact): Contact details for partnerships, support, and enterprise conversations. ## Machine-Readable Files - [llms.txt](https://manusights.com/llms.txt): Curated machine-readable summary of the site. - [llms-full.txt](https://manusights.com/llms-full.txt): Full machine-readable site index. - [robots.txt](https://manusights.com/robots.txt): Crawler policy for search engines and AI bots. - [sitemap.xml](https://manusights.com/sitemap.xml): Machine-readable sitemap of public pages. ## Optional - [Privacy Policy](https://manusights.com/privacy): Full privacy and data-handling policy. - [Terms of Service](https://manusights.com/terms): Service terms and conditions.