Reference notes
Coverage
57 journals
Sources
Journal Intelligence Dataset · publisher-instruction snapshot
Last reviewed
Dataset: 2026-03-30 · verify live instructions
Prepared by the Manusights editorial team.
Submission package reference
Journal Submission Specifications: Word Limits, Figure Limits & Reference Caps
Journal submission requirements by journal vary much more than most authors expect, from NEJM's strict 3,000-word cap and 35-reference limit to PLOS ONE and eLife with no hard limits at all. This reference page replaces scattered author-instructions tabs with one searchable comparison table.
This table covers 33 journals. Word counts are for the main text unless otherwise noted and typically exclude abstract, methods, references, and figure legends, but definitions vary by journal. Always verify against current author instructions before submission.
Quick orientation
Use this page when the journal shortlist is set and the question is whether the package fits the format constraints.
Search, sort, and export submission limits across 33 journals, including word limits, abstract format, figure allowances, reference caps, and supplementary-material rules.
Important note
These are working reference values based on published author instructions as of early 2026. Always verify what the journal counts in the word limit and confirm current figure and reference limits on the live author-instructions page before submission.
10
Strict ≤3,000w
14
Moderate 3–6k words
7
Flexible 6k+ or none
16
Structured abstract
Journal submission requirements by journal
Filter by journal or format rule. Export the current view while building a submission-ready checklist for your manuscript.
| Journal | Article type | Word limit | Figures / tables |
|---|---|---|---|
| Nature | Primary research | ~3,000 (main text) | 6 display items |
| Science | Primary research | ~4,500 | 6–8 display items |
| Cell | Primary research | ~6,000–8,000 | 7–8 main figures |
| New England Journal of Medicine | Primary research | ~3,000 | 5 total |
| The Lancet | Primary research | ~3,000 | 5 total |
| JAMA | Primary research | ~2,800 | 5 total |
| Nature Medicine | Primary research | ~3,000–5,000 | 6 display items |
| Cancer Cell | Primary research | ~6,000–8,000 | 7 main figures |
| Journal of Clinical Oncology | Primary research | ~4,000 | 5 total |
| Circulation | Primary research | ~4,000 | 6 total |
| European Heart Journal | Primary research | ~4,000 | 6 total |
| JACC | Primary research | ~5,000 | 7 total |
| JAMA Oncology | Primary research | ~2,800 | 5 total |
| The Lancet Oncology | Primary research | ~3,000 | 5 total |
| The BMJ | Primary research | ~3,400 | 6 total |
| Brain | Primary research | ~4,000 | 6 total |
| Cell Host & Microbe | Primary research | ~5,000–7,000 | 7 main figures |
| Cell Stem Cell | Primary research | ~5,000–7,000 | 7 main figures |
| Circulation Research | Primary research | ~5,000 | 6 total |
| Current Biology | Primary research | ~4,500 | 6 main figures |
| Developmental Cell | Primary research | ~5,000–7,000 | 7 main figures |
| eLife | Primary research | No strict limit | No strict limit |
| The EMBO Journal | Primary research | No strict format limitation | Usually up to 10 main figures |
| JAMA Cardiology | Primary research | ~2,800 | 5 total |
| Journal of Neuroscience | Primary research | ~10,000 | 10 total |
| Lancet Infectious Diseases | Primary research | ~3,000 | 5 total |
| Lancet Neurology | Primary research | ~3,000 | 5 total |
| Molecular Psychiatry | Primary research | ~4,000 | 6 total |
| Nature Chemical Biology | Primary research | ~3,000 | 6 display items |
| Nature Neuroscience | Primary research | ~3,500 | 8 display items |
| Nature Structural & Molecular Biology | Primary research | ~3,000 | 6 display items |
| PLOS Medicine | Primary research | ~3,000 | 5 total |
| Science Translational Medicine | Primary research | ~4,500 | 8 display items |
Patterns worth knowing
Patterns worth knowing
Submission specs are not arbitrary trivia. They often reveal what kind of paper the journal expects and how much narrative or evidentiary compression the editors assume.
The 3,000-word club
The most prestigious clinical journals (NEJM, Lancet, JAMA, BMJ) are also some of the most restrictive on word count. Their 3,000-word limit covers the body text only; methods, abstract, references, and figure legends sit on top. The practical ceiling for a submission-ready manuscript to these journals is closer to 7,000–8,000 words total.
Cell Press vs. Nature: different philosophies
Cell Press journals (Cell, Neuron, Immunity, Cancer Cell) allow 6,000–8,000 word articles with extensive supplementary data: they expect full mechanistic stories. Nature family journals (Nature, Nature Medicine, Nature Genetics) cap main text at around 3,000 words but allow extensive supplements. Same prestige tier, opposite length philosophy.
Reference limits matter most at clinical journals
JAMA's 35-reference limit is strict and enforced. NEJM allows 70. Many basic science journals (PNAS, Genome Biology, eLife) have no limit. If you're coming from a basic science background and submitting to a clinical journal for the first time, the reference cap is the adjustment that catches most authors off guard.
Open-access journals are generally more flexible
PLOS ONE, eLife, Scientific Reports, BMJ Open, and BMC Medicine don't impose strict word or figure limits. This isn't lower standards. It's a different philosophy. The page cost concern that drove strict limits at traditional print journals simply doesn't apply when publication is digital and costs are covered by APCs.
Word counts, reference caps, and figure limits are mechanical, easy to miss, and a common reason editors return a paper unread. Use the manuscript submission checklist and then confirm every volatile requirement on the journal’s official instructions page.
References
These sources cover the publisher and editorial policies behind the submission limits summarized above.
- International Committee of Medical Journal Editors (ICMJE). Recommendations for the Conduct, Reporting, Editing, and Publication of Scholarly Work in Medical Journals. Updated 2023. [icmje.org ↗]
- Committee on Publication Ethics (COPE). (2017). Core Practices for journal publishers and editors. Retrieved February 2026. [publicationethics.org ↗]
- Springer Nature. Author submission guidelines. Retrieved February 2026. [springernature.com/authors ↗]
- PLOS ONE. Guidelines for authors. Retrieved February 2026. [journals.plos.org ↗]
- Cell Press. Author guidelines: general policies. Elsevier. Retrieved February 2026. [cell.com/author-guidelines ↗]
Version history
February 2026
Reviewed the canonical primary-research specification dataset against current publisher guidance and moved the page onto a single exportable source of truth.
December 2025
Expanded the reference table to 57 journals and assembled the first cross-journal comparison set for submission-limit benchmarking.
Frequently asked questions
Frequently asked questions
What word count limits apply to original research articles at top journals?
Word count limits vary considerably. Nature limits original research articles to 3,000 words of main text. Science allows 4,500 words. Cell allows 6,000-8,000 words depending on article type. NEJM original articles are capped at 3,400 words. JAMA research articles allow 3,000 words. Nature Communications and Scientific Reports are more permissive at 5,000-8,000 words. Always check the current author instructions for your specific article type - Brief Communications, Letters, and Short Reports have tighter limits than full Research Articles.
How many figures and tables are typically allowed?
Most top journals limit main-text figures to 5-6 for Letters or Brief Communications and 6-8 for full Research Articles. Nature allows 5 figures or tables in the main text; additional data can go in Extended Data (up to 10 items). Cell allows 7 figures. NEJM typically allows 4-5 tables or figures in the main text. Additional figures and tables belong in Supplementary Information. Reviewers and editors pay close attention to whether main-text figures are all essential - unnecessary figures are a common revision target.
What file formats do journals accept for manuscript and figure submission?
Most journals accept manuscripts in Microsoft Word (.docx) or LaTeX format via submission systems like Editorial Manager or ScholarOne. For figures, high-resolution TIFF (300-600 DPI for photographs, 600-1200 DPI for line art) is the most widely accepted format. PDF and EPS are also commonly accepted. Avoid low-resolution figures - they are a common cause of revision requests. For revision submissions, many journals also accept a tracked-changes Word document alongside the clean version.
Cite this resource
Citation formats
Free to use and cite, with attribution. See the reuse policy for what you may republish.
- APA
- Manusights. (2026). Biomedical journal submission specifications: Word limits, figure limits, and reference caps (Journal Intelligence Dataset snapshot March 30, 2026). https://manusights.com/resources/journal-submission-specs
- MLA
- Manusights. "Biomedical Journal Submission Specifications: Word Limits, Figure Limits, and Reference Caps." Manusights, Journal Intelligence Dataset snapshot Mar. 30, 2026, manusights.com/resources/journal-submission-specs.
- Vancouver
- Manusights. Biomedical journal submission specifications: word limits, figure limits, and reference caps [Internet]. Journal Intelligence Dataset snapshot 2026 Mar 30. Available from: https://manusights.com/resources/journal-submission-specs
Related guides in this collection