JCI Insight AI Policy: ChatGPT and Generative AI Disclosure Rules for JCI Insight Authors

Acceptable disclosure language for JCI Insight submissions:

"For our translational research-focused manuscript at JCI Insight, we used ChatGPT-4o (OpenAI, used in October 2024) to polish English-language phrasing in the Introduction and Discussion sections. We did not use generative AI for data analysis, figure generation, or substantive manuscript content. All authors reviewed and edited the AI-assisted text and take responsibility for the final manuscript."

Or, for AI-assisted code:

"For this JCI Insight submission addressing translational research, initial Python code for the Bayesian regression analysis was drafted with Claude 3.5 Sonnet (Anthropic, used in December 2024). All code was reviewed, modified, and validated by the authors before use; the final version is available at [repository URL]. Statistical inference was performed using the established R package brms."

What does NOT pass JCI Insight's desk-screen:

• For JCI Insight addressing translational research: "AI tools were used in manuscript preparation." Too vague for the publisher editorial review of JCI Insight submissions; the JCI Insight editorial team needs the specific tool name, version, and specific use case

• "We acknowledge AI assistance in the Acknowledgments." (The journal asks for an AI disclosures paragraph in the Manuscript information section, not the Acknowledgments.)

• "ChatGPT helped write this paper." (Insufficient detail on use case)

• No disclosure when AI was used (a required disclosure is missing)

For JCI Insight-targeted manuscripts, the patterns below are common AI-policy risk areas to check against the publisher's current guidance before submission. Of the manuscripts we screened in 2025 targeting JCI Insight and peer venues, the patterns below are the ones we check against the journal's published AI guidelines.

AI disclosure missing despite obvious AI-assisted phrasing. Substantive AI-assisted drafting without a required disclosure can trigger an editorial query. Check whether your manuscript reads as AI-assisted

AI disclosure placed in the wrong manuscript location. JCI Insight asks for the disclosure in a paragraph titled AI disclosures in the Manuscript information section, so a disclosure placed in Methods or the Acknowledgments is in the wrong location. A misplaced disclosure can create an avoidable submission query. Check whether your AI disclosure is in the right section

Generic disclosure language without tool name and version. JCI Insight requires the task performed, the name and version of the AI tool, and the date or range of dates of use. "AI tools were used" without specifics does not meet that requirement. Check whether your AI disclosure has the required specificity

Source: JCI Insight journal metrics page (accessed 2026-10-09) and Manusights internal review of JCI Insight-targeted submissions, 2025 cohort.

The publisher's AI policy framework continues to evolve as 2026 brings new ICMJE recommendations, COPE guidance refinements, and journal-specific clarifications. JCI Insight authors targeting translational research submissions should track three signals throughout 2026:

Policy updates from the journal. The journal's author pages carry the current AI guidelines, and its revised-submission instructions include worked example disclosures, so recheck both before each submission and each revision. JCI Insight authors who pre-register their disclosure language at submission time tend to face fewer revisions during the 2026 transition period than authors who write boilerplate disclosures.

Field-specific clarifications for translational research. Different research domains see different AI use patterns. The journal's guidelines do not distinguish "substantive" from "ancillary" AI use; they ask for explicit description of generative AI used for written or visual content. Authors who err on the side of more disclosure rather than less avoid the publication-ethics gray zone.

Reviewer rules. JCI Insight does not permit peer reviewers to use AI technologies to write reviews, and its publication-ethics page says reviewers are strictly prohibited from using generative AI to assist with the content of reviews.

• Manusights internal preview corpus (150+ JCI Insight-targeted manuscripts, 2025 cohort)

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