Publishing Strategy7 min readUpdated Apr 2, 2026

Applied Sciences-Basel submission guide

Applied Sciences's submission process, first-decision timing, and the editorial checks that matter before peer review begins.

Senior Researcher, Oncology & Cell Biology

Author context

Specializes in manuscript preparation and peer review strategy for oncology and cell biology, with deep experience evaluating submissions to Nature Medicine, JCO, Cancer Cell, and Cell-family journals.

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Submission at a glance

Key numbers before you submit to Applied Sciences

Acceptance rate, editorial speed, and cost context — the metrics that shape whether and how you submit.

Full journal profile
Impact factor2.5Clarivate JCR
Acceptance rate~50-60%Overall selectivity
Time to decision~60-90 days medianFirst decision
Open access APC~$1,800-2,200Gold OA option

What acceptance rate actually means here

  • Applied Sciences accepts roughly ~50-60% of submissions — but desk rejection runs higher.
  • Scope misfit and framing problems drive most early rejections, not weak methodology.
  • Papers that reach peer review face a different bar: novelty, rigor, and fit with the journal's editorial identity.

What to check before you upload

  • Scope fit — does your paper address the exact problem this journal publishes on?
  • Desk decisions are fast; scope problems surface within days.
  • Open access publishing costs ~$1,800-2,200 if you choose gold OA.
  • Cover letter framing — editors use it to judge fit before reading the manuscript.
Submission map

How to approach Applied Sciences

Use the submission guide like a working checklist. The goal is to make fit, package completeness, and cover-letter framing obvious before you open the portal.

Stage
What to check
1. Scope
Manuscript preparation
2. Package
Submission via MDPI system
3. Cover letter
Editorial assessment
4. Final check
Peer review

Quick answer: Sciences Applied Sciences is a broad MDPI journal, so the biggest submission risk is not the portal itself. It is sending a paper that looks generic, under-characterized, or too theoretical for a journal that wants practical application. If you are submitting there, make the engineering problem explicit, show realistic validation, and be ready to justify why the work belongs in a multidisciplinary applied venue instead of a narrower specialist journal.

From our manuscript review practice

Of manuscripts we've reviewed for Applied Sciences (Basel), application case stated but not operationally validated is the most consistent desk-rejection pattern. Papers where the application is framed in the introduction but validation uses idealized conditions rather than reflecting actual operational environments are returned.

Applied Sciences Key Submission Requirements

Requirement
Details
Submission system
Article types
Research Article, Review, Communication, Letter
APC
Yes; open-access journal with per-article processing charge
Scope
Applied science and engineering across all disciplines
Cover letter
State the practical problem, technical advance, and journal fit
Special issues
Available; confirm scope match with guest editor framing

Before you open the submission portal

Use this checklist before you upload anything:

  • make the application case obvious in the title, abstract, and first page
  • confirm that the results are validated under conditions that look relevant to the real use case
  • prepare a cover letter that states the practical problem, the technical advance, and why Applied Sciences is the right venue
  • double-check author affiliations, funding, and data-availability details before you enter the system
  • gather figure files, supplementary material, and any reporting checklists you plan to submit alongside the manuscript

If the paper still reads like a laboratory proof of concept without a convincing implementation angle, pause before submission. Applied Sciences can be broad, but it is not a home for work that feels disconnected from a real engineering or applied-science problem.

Step-by-step submission flow

The actual submission flow through MDPI's portal is straightforward once the manuscript package is ready. The harder part is making sure the paper is genuinely prepared before the upload begins. Authors who start with a complete, application-focused package move through the portal quickly. Authors who use the portal to figure out whether the paper is ready create avoidable friction at every step. The steps below assume the package is already in good shape.

1. Pick the article type and special issue carefully

Applied Sciences runs many special issues. That can help if the fit is real, but it can also create lazy submissions. Do not choose a special issue just because it looks close enough. Make sure the scope and guest-editor framing actually match the manuscript. If the paper is stronger as a regular article, submit it that way.

2. Build the manuscript around the application case

Before the portal opens, make sure the abstract answers three questions immediately:

  • what practical problem is being solved
  • what technical advance makes the paper different
  • what evidence proves the solution is credible

That is especially important in a journal with broad scope, because editors need a fast reason to believe your paper belongs in their queue.

3. Prepare the cover letter with fit, not flattery

Your cover letter should be short and concrete. State:

  • the application area
  • the engineering or applied-science advance
  • why the findings matter outside a narrow lab context
  • why Applied Sciences is the right audience

Avoid generic claims like “this work will interest your readers.” Name the actual reader group instead.

4. Upload complete files the first time

The fastest way to create delay is a sloppy package. Upload:

  • main manuscript
  • figures in the required format
  • supplementary files
  • data/code availability statement if relevant
  • funding and conflict disclosures

Do not assume the journal will let small inconsistencies slide. Broad journals still screen for basic professionalism.

5. Re-read the generated submission PDF before final approval

On journals with a busy editorial workflow, formatting mismatches, missing symbols, and bad figure ordering can easily slip in during upload. Always review the system-generated proof before final submission. Check that figure captions match the figures, that supplementary file cross-references are correct, that equation symbols rendered properly, and that author affiliations and funding lines are accurate. A submission that looks clean in the source files can still arrive at the editor with garbled tables or missing figure panels.

Common mistakes and avoidable delays

The common avoidable problems are usually predictable:

  • the manuscript sounds more like basic science than applied research
  • the validation is too narrow to support the practical claims
  • the cover letter does not explain why this belongs in Applied Sciences specifically
  • figures show technical performance but not comparison with a realistic baseline
  • the package omits a clear data, code, or supplementary-material explanation
  • the authors choose a special issue that is only loosely related to the paper

One more pattern matters here: some authors send a paper rejected from a more selective materials or engineering journal without changing the framing. That is a mistake. The paper may still fit Applied Sciences, but only if you rewrite it for the journal’s practical and multidisciplinary audience.

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How to decide between a special issue and a regular submission

Applied Sciences runs a high volume of special issues, and that creates a real strategic choice.

Submit to a special issue only if:

  • the topic statement matches the manuscript closely
  • the guest editor group makes sense for the paper
  • the paper benefits from being read next to a focused set of related submissions

Choose a regular submission if:

  • the special issue fit is only partial
  • the paper is broad enough to stand on its own
  • the special issue language is forcing you to oversell a theme that is not the manuscript's real strength

This matters because a weak special-issue fit can make the paper look opportunistic. Editors and reviewers notice quickly when a paper has been dropped into a topical bucket without a convincing reason.

What a submission-ready package should look like

Before you click final submit, the package should look complete from three angles. Editors at broad applied journals make quick triage decisions, and a package that reads as consistent and professional from the first page makes that decision easier. The table below describes what editors are looking for in each dimension.

Package dimension
What a strong submission shows
Common gap
Editorial fit
The title, abstract, and cover letter make the same case about why the work belongs in an applied, multidisciplinary venue; an editor outside the specific subfield can identify the practical problem and the advance without specialized knowledge
Title focuses on technical detail while the abstract and cover letter frame different problems, leaving the editor uncertain about the actual contribution
Technical credibility
Figures and methods show more than proof-of-concept performance; the application case is supported by validation under conditions that reflect real use rather than idealized lab settings
Experimental results are strong in controlled conditions but the paper does not address how performance holds under realistic noise, variability, or operational constraints
Professional execution
Files are clean, supplementary material is intentional and clearly cross-referenced, and the data and code statement is specific rather than generic
Supplementary material feels like a dump of extra figures; data availability statement is vague; broad journals still reject or delay papers that feel rushed, even when the underlying work is solid

What editors and reviewers will notice first

Editors will notice the fit signal before they notice your effort. On a first pass, they will usually ask:

  • is the application case clear from page one
  • is the technical contribution more than a small parameter tweak
  • are the experiments or benchmarks strong enough for the claims
  • does the paper speak to a real applied-science audience

Reviewers will then focus on whether the work is complete enough to support practical use. In this journal, that often means:

  • better benchmark comparisons
  • stronger characterization
  • more honest limits
  • clearer explanation of implementation constraints

If your work is best described as exploratory or conceptual, say that honestly and narrow the claims. Overclaiming utility is a fast way to lose trust in review.

What reviewers are likely to challenge

For this journal, the first round of reviewer pressure usually lands in a few familiar places:

  • whether the benchmark comparison is fair and current
  • whether the validation environment is realistic
  • whether the claimed application is broader than the evidence supports
  • whether the paper explains implementation limits clearly enough

That means the strongest version of the manuscript is usually the one that is slightly more restrained, slightly better benchmarked, and much clearer about what the method or system can and cannot do.

How to make the paper look journal-ready on first read

For a broad applied journal, presentation matters more than many authors assume. A strong Applied Sciences package usually makes four things clear immediately:

  • what real-world problem the paper is solving
  • what the technical contribution adds beyond a routine parameter improvement
  • how the method or system was validated against a relevant baseline
  • what the limits are if a reader tried to use the result in practice

If any one of those is still fuzzy, the paper often reads as competent but not editorially convincing. Tightening that first-read experience can matter as much as another small experimental addition.

Submit If

  • the paper solves a real applied problem and says so clearly
  • the validation is strong enough for a skeptical engineering reader
  • the package is written for a multidisciplinary applied audience
  • the comparison and limitation sections are honest and complete

Think Twice If

  • the application case is still mostly hypothetical or validated only under idealized lab conditions
  • the technical gain is incremental without a clear engineering advantage or mechanistic explanation
  • the paper was rejected from a more selective journal and resent without reframing for a practical audience
  • the manuscript reads more like basic science or materials characterization than applied engineering

Think Twice If

  • the application case is still mostly hypothetical
  • the technical gain is incremental and not clearly useful
  • the paper really belongs in a narrower specialist venue
  • the current draft still reads like a redirect from a rejected higher-tier journal

Bottom line

Applied Sciences can be a reasonable target if your paper solves a real applied problem, validates the solution credibly, and is written for an engineering audience that cares about implementation rather than theory alone. It is a weaker target if the paper mainly reports interesting technical behavior without a convincing application case.

If you are still unsure whether the paper is framed strongly enough, compare it with our How to Choose the Right Journal for Your Paper (A Practical Guide) and 10 Signs Your Paper Isn't Ready to Submit (Yet) before you upload.

Before you upload, run your manuscript through a Applied Sciences submission readiness check to catch the issues editors filter for on first read.

Fast editorial screen table

If the manuscript looks like this on page one
Likely editorial read
Applied problem, technical gain, benchmark, and implementation limit are all visible immediately
Stronger Applied Sciences fit
Engineering work is competent, but the real-world use case is still mostly hypothetical
Too soft for this journal
Technical claim is interesting, but the gain over baseline still feels incremental
Harder editorial case
Application framing is broad while the validation environment stays narrow
Exposed before review

In our pre-submission review work

In our pre-submission review work with manuscripts targeting Applied Sciences (Basel), five patterns generate the most consistent desk rejections worth knowing before submission.

According to Applied Sciences (Basel) submission guidelines, each pattern below represents a documented desk-rejection trigger; per SciRev data and Clarivate JCR 2024 benchmarks, addressing these before submission meaningfully reduces early-rejection risk.

  • Application case stated but not operationally validated (roughly 35%). The Applied Sciences author guidelines require that submissions demonstrate a clear applied-science or engineering contribution with results validated under conditions that reflect a real use case. In our experience, roughly 35% of desk rejections involve manuscripts where the application case is framed in the introduction but the experimental validation uses idealized conditions that do not reflect the actual operational environment of the claimed application. Editors consistently flag submissions where the practical case is stated rather than demonstrated, because a broad applied journal still expects the application to be grounded in results rather than projected from laboratory performance.
  • Benchmark comparison missing or too narrow for the claim made (roughly 25%). In our experience, roughly 25% of submissions present a technical advance without a quantitative comparison against existing methods, systems, or baselines that would allow the editor to assess how the result positions relative to current practice. Editors consistently reject manuscripts where performance claims are made in general terms without naming the specific methods or benchmarks the advance is being compared against, because Applied Sciences readers come from engineering and applied-science fields where comparative context is necessary to evaluate practical relevance.
  • Special issue chosen for topical proximity rather than scope fit (roughly 20%). In our experience, roughly 20% of submissions to special issues have been matched to a thematic cluster based on keyword proximity rather than a genuine overlap between the manuscript's contribution and the special issue's organizing question. In practice editors consistently screen for submissions where the paper adds to the special issue's argument rather than simply fitting into its general topic area, because a weak special-issue fit signals that the submission was opportunistic rather than purposeful.
  • Paper resubmitted without reframing for applied audience (roughly 15%). In our experience, roughly 15% of submissions arrive with framing and tone that reflect the expectations of a more fundamental or higher-tier journal rather than a multidisciplinary applied venue, often because the manuscript was recently rejected elsewhere and sent to Applied Sciences without adaptation. Editors consistently flag papers where the introduction and discussion are written for a specialist readership rather than for engineers and applied scientists across disciplines, because the journal's breadth requires that the paper explain its practical relevance to readers outside the specific research area.
  • Cover letter generic without a multidisciplinary argument (roughly 10%). In our experience, roughly 10% of submissions arrive with cover letters that describe the technical content without explaining why the paper belongs in a broad applied-science journal rather than a narrower specialist venue in the author's field. Editors consistently screen cover letters for a clear answer to the question of which applied-science community beyond the authors' own will benefit from the work and why a multidisciplinary venue is the right home for the contribution.

SciRev author-reported review times and Clarivate JCR 2024 bibliometric data provide additional benchmarks when planning your submission timeline.

Before submitting to Applied Sciences (Basel), an Applied Sciences submission readiness check identifies whether your application case, benchmark comparisons, and multidisciplinary framing meet the editorial bar before you commit to the submission.

Frequently asked questions

Applied Sciences uses the MDPI online submission portal. Pick the article type and special issue carefully, build the manuscript around the application case, upload figures and supplementary material, enter author affiliations, funding, and data-availability details, then submit. A cover letter should state the practical problem, the technical advance, and why Applied Sciences is the right venue.

Applied Sciences wants papers where the engineering or applied-science problem is explicit, results are validated under realistic conditions, and the work belongs in a multidisciplinary applied venue. The abstract should immediately answer what practical problem is being solved and what technical advance makes the paper different.

Yes, Applied Sciences (Basel) is an open-access journal published by MDPI. Accepted articles require an article processing charge (APC). The journal runs many special issues alongside regular submissions.

Common mistakes include submitting work that reads like a laboratory proof of concept without a convincing implementation angle, choosing a special issue just because it looks close enough rather than matching the scope, and writing a paper that looks generic, under-characterized, or too theoretical for a journal that wants practical application.

References

Sources

  1. 1. Applied Sciences journal homepage, MDPI.
  2. 2. Applied Sciences instructions for authors, MDPI.
  3. 3. MDPI ethics and publication policies, MDPI.

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