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Journal Guides6 min readUpdated Jul 8, 2026

Experimental and Molecular Medicine Impact Factor

EMM's 17.5 JIF rewards mechanism-to-disease translation. Check rank, source basis, and fit before submitting.

By Manusights Editorial Team
Editorial processThe Manusights editorial team researches and maintains our Molecular & Cell Biology guides, drawing on what we see across thousands of pre-submission manuscript reviews.How we work

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Quick answer: The Experimental & Molecular Medicine impact factor is 17.5 as the 2025 Journal Impact Factor in the 2026 Journal Citation Reports release, with a five-year JIF of 17.8, JCI of 2.12, and Q1 rank of 10/328 in the current local JCR row. The metric supports an EMM target only when the manuscript makes the mechanism-to-disease bridge visible, not when translational value is decorative.

Last reviewed: July 8, 2026.

What is the Experimental & Molecular Medicine impact factor?

Impact-factor source note

For Experimental & Molecular Medicine, cite 17.5 as the 2025 JIF in the 2026 JCR release. The local JCR master row lists five-year JIF 17.8, JCI 2.12, Q1 rank 10/328, 25,742 total cites, and ISSN 1226-3613. Recheck Clarivate/JCR or the live Springer Nature metric surface before using the number in formal materials.

Evidence basis: this page was reviewed against Clarivate/JCR context, Springer Nature's EMM title and author pages, the local 2025 JCR master row, SCImago context, public recent-article DOI identity checks, and sibling Manusights EMM pages. The purpose is to help authors decide whether the current metric supports an EMM submission or whether the manuscript needs a stronger disease-mechanism and translational-readiness argument first.

How this page was produced: our analysis of EMM-targeted drafts focuses on whether the title, abstract, disease model, main mechanism figure, validation package, translational claim, and cover letter make one coherent argument. We also check practical author details that affect submission planning: the Nature online submission route at mts-emm.nature.com, the journal's open-access status, the APC-check requirement at acceptance, the ISSN record, and recent EMM article DOI patterns such as 10.1038/s12276-026-01757-5, 10.1038/s12276-026-01758-4, and 10.1038/s12276-026-01759-3.

The practical interpretation is that EMM is a real upper-tier translational medicine journal, not a generic biomedical middle ground.

Experimental and Molecular Medicine impact factor at a glance

Metric
Value
Impact Factor
17.5
5-Year JIF
17.8
JCI
2.12
Quartile
Q1
Category Rank
10/328
Total Cites
25,742
Citable Items
213
Cited Half-Life
4.6 years
Scopus Impact Score 2024
12.18
CiteScore context
15.6
SNIP context
2.26
SJR 2024
4.001
h-index
133
Publisher
Springer Nature
ISSN
1226-3613 / 2092-6413
Submission route
Nature online submission route at https://mts-emm.nature.com
Open-access charge basis
Nature open-access fee page: £3290 / $4690 / €3990, subject to VAT or local taxes
Recent DOI identity checks
10.1038/s12276-026-01757-5, 10.1038/s12276-026-01758-4, 10.1038/s12276-026-01759-3

That places EMM in roughly the top 5% of its JCR category by current rank.

What 17.5 actually tells you

The useful signal here is the combination of a 17.5 JIF and a 17.8 five-year JIF. That tells you the journal's better papers are not just catching a short translational buzz cycle. They keep getting used because they remain relevant at the disease-mechanism level.

The journal's identity matters too. EMM occupies a specific lane: mechanistic biomedical work with a credible disease or therapeutic consequence. It is not a pure basic-science journal, and it is not a clinical outcomes journal either.

That is why the number can feel higher than authors expect for a journal that lives between those worlds. The journal is strong precisely because it does that middle lane well.

The author-planning implication is straightforward: EMM is rarely won by a metric-matching argument alone. A manuscript has to show why the mechanism changes disease understanding, why the model is credible for that disease context, and why the translational consequence is proportionate to the data. If those three pieces are separated across the introduction, results, and discussion, the impact factor can make the target look cleaner than it is.

How has the Experimental and Molecular Medicine impact factor trended?

The JCR row above is the authoritative impact factor on this page. Use the Scopus impact-score sequence below as an open-citation context check for EMM's translational molecular-medicine readership.

Year
Scopus impact score
2014
3.95
2015
5.56
2016
5.56
2017
5.98
2018
4.95
2019
5.37
2020
7.33
2021
11.11
2022
12.50
2023
9.18
2024
12.18

Directionally, the open citation signal is up from 9.18 in 2023 to 12.18 in 2024, and dramatically above the mid-2010s range. That is consistent with a journal that has become more visible as translational and disease-relevant molecular work has become more competitive.

The trend is not perfectly smooth. But the broader line is clear: EMM's citation position is substantially stronger than it was a decade ago.

How should you read EMM ranking context and source boundaries?

The table below separates the current JCR placement from older public rank context. Do not treat older category ranks as the current official rank; use them only to understand why snippets and directories may disagree.

Year
Rank or category signal
Source boundary
Author interpretation
2026 release
Q1, rank 10/328
Current local 2025 JCR master row
Use for current JIF and rank decisions.
2025 public citation context
SJR 5.123 Q1, h-index 154
SCImago public profile
Useful secondary context, not a JCR replacement.
2024 Scopus context
Scopus impact score 12.18, SJR 4.001
Resurchify/Open Scopus-derived context
Helps with trend sense, not official JIF citation.
2023 Nature author page copy
2023 JCR value and 27-day median first-decision copy
Nature author instructions page
Useful for process context, but not the current JIF number.
Older encyclopedia snippets
2022 impact factor and historical editorial data
Wikipedia and similar surfaces
Treat as stale for metric decisions.

Why the number can mislead authors

The common mistake is to read the JIF and assume EMM will take any clean mechanistic paper if the biology is interesting enough.

That is usually not the real bar. EMM works best when the manuscript connects:

  • a molecular mechanism
  • a disease or pathophysiology problem
  • a believable translational consequence
  • a package strong enough to survive outside a narrow specialty niche

If the disease relevance is generic, or the translational angle is mostly aspirational, the fit often weakens quickly.

How EMM compares with nearby choices

Journal / publisher surface
2025 JIF
5-year JIF
JCR rank / category signal
Best for
Springer Nature Experimental & Molecular Medicine
17.5
17.8
Q1, 10/328
Mechanistic biomedical work with disease relevance and a credible translational consequence.
Nature Medicine
52.5
52.5
Q1, 2/328
Practice-shifting or exceptionally broad translational medicine.
Science Translational Medicine
15.6
16.8
Q1, 18/207
Translational work where the field-wide applied consequence is stronger than the molecular-disease story.
Cell Press Molecular Therapy
11.4
12.7
Q1, 10/180
Therapy, delivery, gene, or cell intervention work where modality execution is the center.

That is why EMM can be the right answer for papers that are too translational for a narrow specialist journal and too modest for the highest general-translational tier.

What do our Experimental & Molecular Medicine pre-submission reviews show?

Across our Experimental & Molecular Medicine pre-submission reviews, the recurring problem is not lack of science. It is lack of a clean translational story. Authors often have a mechanism, a disease context, and a hopeful implication, but the manuscript still reads like three parallel claims rather than one integrated argument. EMM usually rewards papers where disease meaning is explicit from the title, abstract, model choice, and first main figure.

Four failure patterns recur.

Experimental & Molecular Medicine omics signal without experimental follow-through. The associations may be strong, but the causal bridge is still too thin. In EMM-targeted drafts, this often shows up as a transcriptomic or proteomic figure that dominates the Results while the functional validation is a short final panel. The methods may be clean, but the abstract starts sounding like a biomarker paper rather than a disease-mechanism paper. Before submission, the main figure set should show what was perturbed, what changed biologically, and why that change matters for the disease model.

Experimental & Molecular Medicine disease framing that stays generic. The manuscript names a disease context without showing why the finding changes disease understanding or therapeutic logic. We see this most often when the introduction uses broad prevalence language, then the Results section never returns to a specific patient subgroup, disease stage, tissue context, or model limitation. EMM readers need the disease claim to survive contact with the methods, not just the final discussion paragraph.

Experimental & Molecular Medicine therapeutic language that outruns the data. This is common when a mechanism paper starts making treatment claims before the validation package justifies them. The cover letter may promise a therapeutic route, while the manuscript only shows pathway association, cell-line rescue, or a limited animal signal. For EMM, the safer version is usually a proportionate translational claim: what the result changes about target logic, patient stratification, or disease mechanism, and what validation still remains.

Experimental & Molecular Medicine story breadth without a sharp throughline. EMM usually prefers a clearer disease-mechanism-translational throughline than manuscripts first arrive with. A draft can have multiple datasets, several supplementary tables, and a plausible disease problem, yet still fail because the title, abstract, first Results subsection, and concluding paragraph each imply a slightly different center of gravity. The fix is not more claims. It is choosing one mechanism-to-disease argument and making every major figure serve it.

If that still sounds like the paper, an Experimental and Molecular Medicine submission readiness check is usually more valuable than cosmetic revision.

How to use this number in journal selection

Use the impact factor to place EMM correctly. It is a serious journal in the translational biomedical tier, and the long-run citation profile supports that.

But do not let the number replace the fit decision. The better question is whether the paper makes disease relevance and translational consequence feel necessary, not optional.

That is the real difference between an EMM submission and a narrower mechanism paper.

What the number does not tell you

The impact factor does not tell you whether the translational bridge in your paper is convincing. EMM still expects the disease consequence to feel earned, not decorated. A mechanistic result plus a paragraph about therapeutic promise is often not enough.

That is where many submissions get misread by their own authors. The citation profile makes the journal look broadly permissive. In practice, the journal is selective about whether mechanism, disease meaning, and translational consequence form one coherent story.

That distinction becomes especially visible on papers built around one attractive dataset but an underdeveloped biomedical argument.

Submit If

  • the manuscript ties mechanism clearly to disease meaning
  • the translational consequence is specific and proportionate to the evidence
  • the paper reads as biomedical and disease-relevant from the title onward
  • the work is stronger than a niche specialist journal fit but not aimed at a flagship general-medicine outlet

Think Twice If

  • the abstract names a disease but the main figures still read as pathway biology without a patient, tissue, or model-specific consequence
  • the omics table or heatmap is the strongest result and the functional methods only test one downstream marker
  • the cover letter promises therapeutic relevance before the manuscript has proportionate validation for that claim
  • the manuscript would be more honest as a narrow mechanism paper in a specialist venue

Should you use the EMM impact factor to choose this journal?

Experimental and Molecular Medicine has an impact factor of 17.5 and a five-year JIF of 17.8. The better signal is the journal's strengthened long-run citation profile in translational biomedical work.

If the disease relevance is still generic, the metric will make the fit look cleaner than it really is.

Already submitted? The Experimental & Molecular Medicine Under Review status guide explains what the current status means and when a follow-up is appropriate.

Frequently asked questions

Experimental & Molecular Medicine has a 2025 Journal Impact Factor of 17.5 in the 2026 Journal Citation Reports release, with a five-year JIF of 17.8.

Yes. EMM is a strong Q1 translational biomedical journal. The useful signal is the combination of a 17.5 JIF, 17.8 five-year JIF, 2.12 JCI, and rank 10/328 in the current local JCR row.

Experimental & Molecular Medicine is published by Springer Nature. The public title record lists ISSN 1226-3613 and online ISSN 2092-6413.

A higher five-year JIF suggests that stronger EMM papers keep being cited beyond the short two-year citation window, which fits durable disease-mechanism and translational biology work.

No. EMM still expects a credible mechanism-to-disease bridge. Pure mechanism without biomedical meaning, or disease language added late, is usually a weaker fit.

The Nature author page routes submissions through the online system at mts-emm.nature.com. Always verify the live author page before upload.

Yes. Nature describes EMM as an open access journal, and accepted manuscripts are subject to an article processing charge. Verify the current APC on the Springer Nature fee page before acceptance.

Common misses include omics-heavy papers without functional follow-through, disease framing that stays generic, therapeutic claims that outrun the validation package, and abstracts that never make the translational consequence concrete.

Cite it as the 2025 Journal Impact Factor in the 2026 Journal Citation Reports release. Use Clarivate/JCR or a current publisher metric surface for formal CV, grant, or promotion materials.

Check whether the title, abstract, main figures, disease model, and cover letter all prove that mechanism, disease meaning, and translational consequence belong together.

References

Sources

  1. Clarivate Journal Citation Reports (2026 JCR release; 2025 Journal Impact Factor data used for the page)
  2. Experimental & Molecular Medicine homepage
  3. Experimental & Molecular Medicine for authors
  4. Experimental & Molecular Medicine about the editors
  5. Experimental & Molecular Medicine open access fees
  6. Experimental & Molecular Medicine online submission
  7. SCImago: Experimental and Molecular Medicine
  8. Resurchify: Experimental and Molecular Medicine (used for the Scopus impact-score trend and SJR context)

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