Journal Guides5 min readUpdated May 16, 2026

IJMS 'Under Review': What Each Status Means and When to Expect a Decision

If your IJMS submission shows Under Review, here is what each status means, how long each stage typically takes, and when to follow up.

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What to do next

Already submitted to International Journal of Molecular Sciences? Use this page to interpret the status and choose the next step.

The useful next step is understanding what the status usually means at International Journal of Molecular Sciences, how long the wait normally runs, and when a follow-up is actually reasonable.

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Timeline context

International Journal of Molecular Sciences review timeline: what the data shows

Time to first decision is the most actionable number. What happens after varies by manuscript and reviewer availability.

Full journal profile
Time to decision~45 days to first decisionFirst decision
Acceptance rate~30%Overall selectivity
Impact factor4.9Clarivate JCR
Open access APC€2,000-2,500Gold OA option

What shapes the timeline

  • Desk decisions are fast. Scope problems surface within days.
  • Reviewer availability is the main variable after triage. Specialized topics take longer to assign.
  • Revision rounds reset the clock. Major revision typically adds 6-12 weeks per round.

What to do while waiting

  • Track status in the submission portal — status changes signal active review.
  • Wait at least the journal's stated median before sending a status inquiry.
  • Prepare revision materials in parallel if you expect a revise-and-resubmit decision.

_Last reviewed: 2026-05-16._

Quick answer: If your IJMS manuscript shows "Under Review," the most reliable signal is elapsed time, not the status label. International Journal of Molecular Sciences has a 2024 JCR impact factor of 4.9, accepts about 50 percent of submissions, and reports a median first-decision time of approximately 17 days, one of the fastest in molecular biology. If you have been Under Review for more than 1 week, you have likely passed admin and the reviewers are working.

Submission portal and editorial contact: IJMS uses MDPI's submission system at susy.mdpi.com (an Editorial-Manager-style submission portal). Editorial questions go to ijms@mdpi.com, referencing your manuscript ID. Note: MDPI also operates a parallel submission interface that some authors reach via Editorial Manager-style URLs such as editorialmanager.com/ijms in legacy flows; the susy.mdpi.com path is canonical. Technical support is reachable at support@mdpi.com or via the Elsevier support team for cross-publisher transfers at support@elsevier.com.

IJMS desk-rejects roughly 30 to 40 percent of submissions, usually within 5 to 10 days. If your paper is still showing "Under Review" after that window, peer review is in progress.

While you wait

You can't speed up IJMS's review. A IJMS submission readiness check flags mechanism-evidence gaps, control-experiment completeness, and statistical-rigor issues that drive most reviewer requests, in about 5 minutes.

IJMS's review pipeline

Status
What is happening
Typical duration
Submitted
Administrative processing
Day 0 to 2
With Editor / Editor Assigned
Editor evaluating desk-screen fit
Days 2 to 7
Under Review
Reviewers invited or actively reviewing
Days 7 to 21
Reviewers Assigned, Awaiting Scores
Reports incoming
7 to 14 days
Decision in Process
Editor finalizing decision
1 to 3 days
Decision Sent
Reject, R&R, or accept
Check email

The editorial desk screen (about 30 to 40 percent rejected)

IJMS editors are evaluating molecular-biology contribution, methodology completeness, and scope fit against the journal's broad molecular-sciences mandate. A desk rejection usually means scope mismatch or methodology gaps that would not survive open peer review.

Day 0: MDPI portal upload

The MDPI susy.mdpi.com portal accepts the package and routes to a handling editor matching the molecular-biology subfield.

Days 1 to 7: Editor desk-screen

The handling editor reads the paper, evaluates scope and methodology, and decides whether to invite reviewers.

Days 7 to 14: Reviewer invitations

IJMS typically invites two reviewers with topic-matched expertise; MDPI's reviewer-recruitment process is fast because of its large reviewer pool and standardized 10-day review turnaround.

Days 14 to 21: Peer review

Reviewer reports return on a 1 to 2 week cadence; the 17-day median first-decision time reflects this.

Days 17 to 21: First editorial decision

Major revision or minor revision are the most common outcomes; outright rejection after review is less common at IJMS than at more selective journals.

Days 21 to 45: Revision rounds and acceptance

Single-revision acceptances run roughly 4 to 6 weeks total; multi-round revisions push closer to 8 weeks.

When to worry

  • Rejection within 1 to 3 days: Administrative issue (missing files, ethics statement) or immediate scope mismatch.
  • Rejection within 5 to 10 days: Desk rejection. Editor concluded the paper does not meet IJMS's methodology bar.
  • Still Under Review after 2 weeks: Normal. Reviewers are working on the standard MDPI 10-day turnaround.
  • Still Under Review after 6 weeks: Unusual for IJMS. Polite inquiry is appropriate.
  • Status changes to "Decision in Process": Reports are in; expect decision within days.

What to do while waiting

  • Do not contact the editorial office during the first 4 weeks unless urgent.
  • Do not submit the same paper elsewhere while Under Review at IJMS.
  • Prepare a point-by-point response template focused on control experiments, statistical methods, and methodological details.
  • If you posted a preprint, continue presenting at conferences; IJMS accepts preprinted submissions.

Readiness check

While you wait on International Journal of Molecular Sciences, scan your next manuscript.

The scan takes about 1-2 minutes. Use the result to decide whether to revise before the decision comes back.

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How IJMS compares to nearby alternatives for status tracking

Feature
IJMS
Molecules
Cells
Cells (MDPI) Molecules vs JBC
Desk rejection rate
30 to 40 percent
30 to 40 percent
30 to 40 percent
varies by venue
Desk decision speed
5 to 10 days
5 to 10 days
5 to 10 days
varies
Status granularity
Moderate
Moderate
Moderate
varies
Total review time
17 days median
14 to 21 days
17 days median
varies
Peer-review model
Single-blind
Single-blind
Single-blind
varies
Editorial bar
Broad molecular-sciences soundness
Broad chemistry-molecular soundness
Broad cell-biology soundness
varies

Submit if your paper passed the desk

If your IJMS paper is Under Review and has been for more than 1 week, you have likely cleared the desk screen.

IJMS submission readiness check. It takes about 1-2 minutes.

For a free pre-upload diagnostic on a future IJMS manuscript, use the IJMS manuscript fit check to surface methodology and control-experiment gaps before reviewers do.

Think twice before assuming "Under Review" means safe

IJMS editors retain discretion to reject after partial review. Our IJMS manuscript fit check flags methodology gaps, missing controls, and weak mechanism evidence before reviewers do.

Last verified: IJMS author guidance, MDPI submission portal at susy.mdpi.com, and editorial contact at ijms@mdpi.com.

IJMS review timeline compared to other broad molecular-sciences venues

Timeline stage
IJMS
Molecules
Scientific Reports
PLOS ONE
Desk decision
5 to 10 days
5 to 10 days
7 to 14 days
14 to 28 days
Desk rejection rate
30 to 40 percent
30 to 40 percent
30 to 40 percent
30 to 40 percent
Peer review period
1 to 2 weeks
1 to 2 weeks
3 to 6 weeks
6 to 12 weeks
First decision (total)
17 days median
14 to 21 days
45 days median
8 to 14 weeks
Revision period
14 to 30 days
14 to 30 days
30 to 60 days
60 to 90 days
Total time to acceptance
2 to 3 months
2 to 3 months
3 to 5 months
5 to 8 months

The IJMS reviewer experience

Reviewer focus area
What IJMS asks reviewers to evaluate
How to prepare for it
Methodology completeness
Are methods appropriate and documented?
Include detailed methods with reagent catalog numbers
Control experiments
Are appropriate controls included?
Include negative and positive controls for each key experiment
Statistical rigor
Are statistical methods appropriate?
Include sample-size justification and multiple-comparison corrections
Mechanism vs description
Does the paper establish mechanism or describe observation?
If claiming mechanism, include perturbation experiments
Reproducibility
Could another lab reproduce this work?
Provide protocols with enough detail for independent replication

What we have seen while authors wait for IJMS decisions

The waiting is informative: if no decision in 2 weeks, peer review is in progress. The most common timeline question is around the 4-week mark; this is at or near the IJMS median for revision decisions.

In our pre-submission review work with IJMS manuscripts

Three failure patterns generate the most consistent rejections.

Mechanism described but not established. Reviewers distinguish observation from established mechanism. The fix is to include perturbation experiments for mechanism claims.

Control experiments missing or weak. IJMS reviewers carefully verify controls. The fix is to include both negative and positive controls for each key experiment.

Statistical analysis insufficient for the claim. Sample-size justification and multiple-comparison correction are routinely flagged. The fix is to include power calculations and correction methods upfront.

Methodology note: how to use this page safely

This page was created from IJMS's public author guidance, MDPI submission portal documentation, and Manusights review work.

Signal you can trust
Signal to ignore
Best action
Elapsed time since submission
Refreshing the same status daily
Compare your wait with the timeline above
A decision email or editor inquiry
Forum guesses about one label
Respond to the actual request
Reviewer comments after decision
Whether the status changed at midnight
Build a point-by-point response plan

Frequently asked questions

Your manuscript has cleared MDPI admin checks and is being evaluated by external peer reviewers. IJMS uses MDPI's submission system and treats 'Under Review' as the active peer-review period.

IJMS reports a median first-decision time of approximately 17 days, one of the fastest in molecular biology. Most decisions land within 2 to 4 weeks of submission.

Wait at least 4 weeks before inquiring. When you do email ijms@mdpi.com, keep it short and factual, reference the manuscript ID.

Reviewers have been invited or are actively reviewing. MDPI typically invites two reviewers and aims for a 10-day review turnaround.

Yes, though it is slower than the median. Mechanism-heavy molecular-biology papers extend the timeline because reviewers verify experimental design.

Past 6 weeks Under Review is unusual for IJMS. A polite inquiry to ijms@mdpi.com is appropriate. Silence in the first 3 weeks is normal.

References

Sources

  1. IJMS journal homepage
  2. MDPI submission system
  3. MDPI editorial process

Best next step

Use this page to interpret the status and choose the next sensible move.

For International Journal of Molecular Sciences, the better next step is guidance on timing, follow-up, and what to do while the manuscript is still in the system. Save the Free Readiness Scan for the next paper you have not submitted yet.

Guidance first. Use the scan for the next manuscript.

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Where to go next

Open Status Guide