Nano Letters Formatting Requirements: Complete Author Guide
Nano Letters limits papers to ~4,000 words with a mandatory TOC graphic (3.25 x 1.75 inches). ACS numbered reference style with superscript citations, and substantial Supporting Information is expected.
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Specializes in manuscript preparation and peer review strategy for oncology and cell biology, with deep experience evaluating submissions to Nature Medicine, JCO, Cancer Cell, and Cell-family journals.
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Quick answer: Nano Letters limits papers to approximately 4,000 words of body text, requires a mandatory TOC graphic (3.25 x 1.75 inches), uses the ACS numbered reference style, and expects substantial Supporting Information. Published by ACS, the journal covers all areas of nanoscience and has an impact factor above 9.
Word and page limits by article type
Nano Letters is a high-impact letters journal published by the American Chemical Society (ACS). It publishes only short communications focused on nanoscience and nanotechnology.
Article Type | Word Limit | Abstract Limit | Figures | TOC Graphic |
|---|---|---|---|---|
Letter | ~4,000 words | 200 words | No formal cap (typically 4-5) | Required |
Perspective (invited) | ~5,000 words | 200 words | No formal cap | Required |
Mini Review (invited) | ~6,000 words | 200 words | No formal cap | Required |
The 4,000-word limit covers body text only. Abstract, references, figure captions, and Supporting Information are excluded. This gives you roughly 5-6 double-spaced pages of text. For a journal with an impact factor above 9, the bar for what goes into those 4,000 words is extremely high.
Nano Letters receives approximately 10,000 submissions per year and accepts around 18-20%. The journal is competitive, and the editors are selective about both scientific quality and scope. Manuscripts that are primarily synthetic reports without mechanistic insight or broader implications are routinely desk-rejected.
The letter format means you need to be strategic. Present your strongest results in the main text. Move supporting data, controls, and detailed methods to the Supporting Information. Reviewers understand this structure and expect it.
One thing to know: Nano Letters doesn't have a distinct "communication" versus "article" format. Everything is a Letter. If your work needs more space than 4,000 words for the main narrative, ACS Nano (same publisher, full-length articles) is the natural alternative.
Abstract requirements
Nano Letters follows ACS abstract conventions.
- Word limit: 200 words maximum
- Structure: Unstructured single paragraph
- Citations: Not allowed
- Keywords: Not required by the journal; ACS handles subject indexing
- TOC entry: The abstract text also serves as the TOC entry (accompanied by the TOC graphic)
The abstract should be self-contained and describe the main finding with specific quantitative outcomes. For Nano Letters, the abstract often determines whether a reader opens the full paper. State what you made or measured, what you found, and why it matters, all within 200 words.
ACS journals treat the abstract as a standalone document. Abbreviations defined in the abstract must be redefined in the body text. Don't reference figures, tables, or equations in the abstract.
Figure and table specifications
Figures are the visual backbone of Nano Letters papers. The journal is image-rich, and high-quality figures are expected.
Figure specifications:
Parameter | Requirement |
|---|---|
Minimum resolution (line art) | 600 dpi |
Minimum resolution (photographs/TEM/SEM) | 300 dpi |
Minimum resolution (combination) | 600 dpi |
Accepted formats | TIFF, EPS, PDF, PNG, JPEG |
Color mode | RGB for online |
Single column width | 3.33 in (8.46 cm) |
Double column width | 6.83 in (17.35 cm) |
Font in figures | Arial or Helvetica, 6-8 pt |
Maximum figure width | 6.83 in |
There's no formal figure cap, but the 4,000-word limit constrains space. Most Nano Letters papers include 4 to 5 figures in the main text, with additional figures in the Supporting Information. Multi-panel figures are standard. A single figure with panels (a) through (f) is typical for nanoscience papers that combine synthesis, characterization, and performance data.
TOC graphic (mandatory):
Parameter | Specification |
|---|---|
Width | 3.25 in (8.25 cm) |
Height | 1.75 in (4.45 cm) |
Resolution | 600 dpi minimum |
Format | TIFF, EPS, PDF, PNG |
Background | White preferred |
The TOC graphic should visually communicate the essence of the paper at a glance. For Nano Letters, effective TOC graphics typically show a nanostructure image alongside a key data plot or a schematic of the phenomenon. Avoid text-heavy graphics. The graphic will be displayed at small sizes in the table of contents, so clarity at reduced dimensions is essential.
Color is free at ACS. Use it. Nano Letters papers without color figures are rare. TEM/SEM micrographs, optical spectra, device curves, and schematics all benefit from color.
Reference format
Nano Letters uses the standard ACS citation style.
In-text citations: Superscript numbers: ^1, ^2, ^1,2, ^1-3. Sequential numbering based on first appearance.
Reference list format:
(1) Author, A. B.; Author, C. D.; Author, E. F. Title of Article. J. Abbrev. Name Year, Volume, Pages.Key formatting details:
- Author names: Surname, initials (e.g., "Smith, J. K.")
- Semicolons between authors
- Article titles included, in title case
- Journal names abbreviated per CAS Source Index (CASSI) standards
- Year in bold, followed by volume in italic
- Page range or article number
- DOI at the end: DOI: 10.xxxx/xxxxx
ACS style is well-supported by citation managers. Zotero, Mendeley, and EndNote all have ACS styles. The main thing to verify is that journal abbreviations follow CASSI conventions, not PubMed or ISO 4 abbreviations.
Reference counts for Nano Letters papers typically range from 25 to 40. There's no formal cap, but the letter format naturally constrains citations. Cite the most relevant work directly and move extended literature surveys to the Supporting Information if needed.
Supplementary material guidelines
Supporting Information (SI) is functionally mandatory for Nano Letters papers, even though it's not formally required.
What goes in the SI:
- Detailed experimental procedures (synthesis, fabrication, measurement protocols)
- Full characterization data (TEM, SEM, XRD, XPS, NMR, FTIR)
- Control experiments and additional data
- Computational details (DFT methods, parameters, convergence tests)
- Additional figures and tables
- Videos (device operation, dynamic processes)
The SI is submitted as a separate PDF (plus video files if applicable) through the ACS Paragon Plus submission system. It goes through full peer review. Reviewers frequently request additional SI during revision.
ACS requires a brief description of the SI in the main text, typically one or two sentences before the references: "Supporting Information: Additional characterization data, experimental details, and Figures S1-S10."
Data deposition: For crystallographic data, deposit CIF files with the Cambridge Crystallographic Data Centre (CCDC). For genomic or proteomic data, use appropriate public repositories. ACS doesn't have its own data repository but encourages deposition in Figshare or institutional repositories.
The SI for Nano Letters papers is often substantial, running 15-30 pages for a thorough experimental study. This is normal and expected. Reviewers want to see the data even if it doesn't fit in the main text.
LaTeX vs Word: what Nano Letters actually prefers
ACS accepts both, and the nanoscience community is split.
Word: The ACS Word template is available from the ACS author guidelines page. It provides formatting for all ACS journals, with journal-specific options.
LaTeX: The achemso package is the standard for ACS journals. Use \documentclass[journal=nalefd,manuscript=letter]{achemso} for Nano Letters. The package handles reference formatting, section structure, and journal-specific layout. It's available on CTAN and Overleaf.
In nanoscience, the Word/LaTeX split is roughly 50/50. Materials science and chemistry groups tend toward Word; physics-leaning nanoelectronics and nanophotonics groups tend toward LaTeX. ACS's production system handles both without preference.
Initial submission: ACS Paragon Plus accepts a single PDF for the initial submission. At revision, you'll need source files (.docx or .tex) plus high-resolution figure files. Keep your originals organized.
One LaTeX-specific note: the achemso package automatically formats the TOC graphic entry if you use the \tocentry command. This saves formatting headaches.
Journal-specific formatting quirks
These are Nano Letters-specific details experienced authors know:
TOC graphic is mandatory and scrutinized. The editorial office checks for the TOC graphic at submission and returns papers without one. Beyond compliance, the TOC graphic affects visibility. A well-designed graphic can increase click-through rates from the table of contents significantly.
No structured sections required. Nano Letters doesn't mandate specific section headings (Introduction, Methods, Results, Discussion). Many authors use no section headings at all, writing the paper as a continuous narrative. Others use brief descriptive headings. The choice is yours, but the continuous narrative style is more traditional for this journal.
Associated Content section. Before the references, include an "Associated Content" section that describes the Supporting Information contents. Also include an "Author Information" section with corresponding author email, ORCID iDs, author contributions, and conflict of interest disclosures.
ORCID iDs. ACS requires the corresponding author to have an ORCID iD linked to their ACS Paragon Plus account. Co-authors are strongly encouraged to link their ORCIDs.
Safety information. If your work involves hazardous materials, high-pressure systems, or other safety-relevant procedures, ACS requires a safety statement in the main text. This is increasingly enforced for nanomaterials synthesis involving toxic precursors.
Cover art suggestions. Nano Letters occasionally features article images on the journal cover. If you believe your work has visually compelling imagery, you can submit a cover suggestion alongside your manuscript.
Preprint policy. ACS allows preprints (e.g., on ChemRxiv or arXiv) without restriction. This is worth knowing because some competing journals still have limitations.
Frequently missed formatting requirements
These get flagged in Nano Letters submissions:
- TOC graphic wrong dimensions. The 3.25 x 1.75 inch specification is precise. Graphics with wrong aspect ratios get returned. Create at exactly the required dimensions.
- SI not cited in text. Every SI figure and table must be referenced in the main text. Orphaned SI content will be flagged.
- Missing characterization data. For papers reporting new nanomaterials, reviewers expect full characterization covering size distribution, crystal structure, composition analysis, and stability data. Missing any of these is a common revision trigger.
- Safety statement absent. If your synthesis uses HF, cadmium compounds, lead compounds, or other notably hazardous chemicals, a safety statement is required.
- Abstract exceeding 200 words. The ACS Paragon Plus system will flag abstracts over the limit. Edit before submission.
Submission checklist
Before submitting to Nano Letters, verify:
- Body text is under 4,000 words (excluding abstract, references, captions, SI)
- Abstract is 200 words or fewer, unstructured, no citations
- TOC graphic is 3.25 x 1.75 inches at 600+ dpi
- Figures are 300+ dpi with clear labels and scale bars where applicable
- References use ACS numbered style with DOIs
- Supporting Information covers experimental details and full characterization
- Associated Content section describes SI contents
- Author Information section includes ORCID iDs and conflict disclosures
- Safety statement included if hazardous materials are used
Nano Letters' high impact factor means competition is intense. Getting the format right eliminates one variable. If you want to check your manuscript's readiness before submitting, run a free readiness scan to catch the issues that lead to desk rejection at top-tier nanoscience journals.
For the latest guidelines, visit the ACS Nano Letters author guidelines.
If you're comparing nanoscience journals, our guides on understanding impact factors and choosing the right journal can help you decide where your work fits best.
Sources
- 1. Nano Letters, author guidelines, American Chemical Society.
- 2. Clarivate Journal Citation Reports.
Reference library
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Dataset / reference guide
Peer Review Timelines by Journal
Reference-grade journal timeline data that authors, labs, and writing centers can cite when discussing realistic review timing.
Dataset / benchmark
Biomedical Journal Acceptance Rates
A field-organized acceptance-rate guide that works as a neutral benchmark when authors are deciding how selective to target.
Reference table
Journal Submission Specs
A high-utility submission table covering word limits, figure caps, reference limits, and formatting expectations.
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