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Publishing Strategy9 min readUpdated Jun 7, 2026

Rejected from Clinical Infectious Diseases? The 7 Best Journals to Submit Next

Paper rejected from Clinical Infectious Diseases? 7 alternative journals by fit, scope, and review speed, plus the IDSA transfer route to OFID.

Author contextAssociate Professor, Clinical Medicine & Public Health. Experience with NEJM, JAMA, BMJ.View profile

Journal fit

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Journal context

Clinical Infectious Diseases at a glance

Key metrics to place the journal before deciding whether it fits your manuscript and career goals.

Full journal profile
Impact factor7.3Clarivate JCR
Acceptance rate~25-35%Overall selectivity
Time to decision~90-120 days medianFirst decision

What makes this journal worth targeting

  • IF 7.3 puts Clinical Infectious Diseases in a visible tier — citations from papers here carry real weight.
  • Scope specificity matters more than impact factor for most manuscript decisions.
  • Acceptance rate of ~~25-35% means fit determines most outcomes.

When to look elsewhere

  • When your paper sits at the edge of the journal's stated scope — borderline fit rarely improves after submission.
  • If timeline matters: Clinical Infectious Diseases takes ~~90-120 days median. A faster-turnaround journal may suit a grant or job deadline better.
  • If open access is required by your funder, verify the journal's OA agreements before submitting.

Quick answer: If you were rejected from Clinical Infectious Diseases (Oxford University Press / IDSA, JCR 2024 impact factor 7.3, Q1), you are in normal company: CID accepts only about 15 to 20 percent of submissions and desk-rejects many papers within roughly a week, before external review begins, so a rejection here is the normal first outcome, not a dead end. Your best next journal depends on why it was rejected.

For sound clinical work that missed the priority bar, Open Forum Infectious Diseases (the IDSA open-access sister title) is the native step down. For pathogenesis and host-immunity work, the Journal of Infectious Diseases; for diagnostics and clinical microbiology, Clinical Microbiology and Infection; for global and outbreak epidemiology, the International Journal of Infectious Diseases; for broad clinical ID with a public-health angle, Infection; for a fast open-access home, BMC Infectious Diseases.

Before you send the manuscript anywhere, decide whether the rejection was about clinical priority and scope (move journals now) or about generalizability, the clinical-significance claim, or reporting rigor (fix it first, or the next reviewer raises the same point). If CID offered you an IDSA transfer, read the cascade section below before you accept or decline. Run a Clinical Infectious Diseases manuscript fit check to see whether clinical priority or substance was the real problem.

Why Clinical Infectious Diseases rejected your paper

CID is the flagship clinical journal of the Infectious Diseases Society of America, and its editors run a fast, priority-strict desk screen before any external review. The editorial question is narrow: does this work change what a clinician does at the bedside, or how a health system manages infection? Three reasons account for most rejections.

Wrong scope or clinical priority for the journal. CID wants practice-changing original research, reviews, guidelines, and perspectives that clinicians can actually use when caring for patients. It explicitly redirects basic microbiology mechanisms, in vitro-only susceptibility data, animal-model infection studies without clinical applicability, and early-phase assays to the Journal of Infectious Diseases. A large share of rejections is simply a paper landing on the basic-science side of that clinical line.

Limited generalizability dressed as a general finding. A single-center retrospective cohort, framed in the abstract as a broad recommendation but with no external-validity discussion, reads as local audit at a journal whose readers practice across hundreds of different settings. CID editors screen hard for the gap between the data's reach and the manuscript's claim.

Rigor gaps visible at the desk. A clinical claim resting on an underpowered sample, a missing reporting checklist, or a statistical approach that does not match the study design gets filtered before review, because the desk screen cannot separate the reported effect from chance. The detailed, manuscript-testable versions of all three failures are in the rejection-patterns section below.

The 7 best journals to submit next

Journal
Selectivity / fit
Scope
Review speed
Open Forum Infectious Diseases
Most accessible step down; same IDSA family
Clinical, translational, and basic ID with patient-care relevance
Rapid; OA
Journal of Infectious Diseases
Selective; IDSA sister
Pathogenesis, diagnosis, treatment, host immune mechanisms
Moderate
Clinical Microbiology and Infection
Selective; ESCMID flagship
Clinical microbiology, diagnostics, therapy, prevention
Moderate
International Journal of Infectious Diseases
Moderately selective; ISID
Epidemiology, diagnosis, treatment, control; global emphasis
Moderate
Infection
Moderately selective; Springer
Clinically relevant ID; etiology, diagnosis, treatment, public health
Moderate
BMC Infectious Diseases
Accessible; sound-science OA
Prevention, diagnosis, management of human ID
Moderate; OA
Lancet Infectious Diseases
Highly competitive (aspirational)
Practice-changing global and public-health ID
Slow

Source: Clarivate JCR 2024, Oxford Academic, ESCMID, Springer, and the journals' own author guidelines (accessed June 2026). Open-access status noted where relevant; APCs are set per journal and may be waived.

1. Open Forum Infectious Diseases (OFID). This is the in-house IDSA open-access sister title and the most natural landing spot for technically sound clinical work that did not clear the flagship's priority bar. It exists explicitly to give CID-quality work a rapid publication route and accepts transfers directly from CID, so the topical fit is essentially identical, which removes the scope-mismatch risk that sinks cross-society moves. Factor the open-access APC into the decision.

2. Journal of Infectious Diseases (JID). If your work is really about pathogenesis, host immune response, microbial biology, or translational mechanism rather than bedside management, this is the journal CID itself redirects that work to. The fit is strongest when the contribution is mechanistic, not clinical-decision-making.

3. Clinical Microbiology and Infection (CMI). The cleanest specialist alternative when the contribution is a diagnostic assay, an antimicrobial-resistance finding, or a clinical-microbiology question. CMI rewards work that helps physicians and clinical microbiologists manage patients and assess new diagnostics, so it fits diagnostics-led manuscripts that read as borderline-clinical at CID.

4. International Journal of Infectious Diseases (IJID). A good home when the real contribution is epidemiology, control, or outbreak surveillance, with particular openness to diseases common in lower-resource settings. If your study is population-level rather than individual-patient management, IJID frames it well.

5. Infection. Fits broad clinical ID work that spans etiology, diagnosis, and treatment and touches public-health implications. It is a sensible mid-tier clinical venue when the manuscript is solid and clinically relevant but not framed around a single practice-changing decision.

6. BMC Infectious Diseases. The sound-science open-access option: it judges whether the work is methodologically rigorous and adds to the literature, not whether it clears a general-interest priority bar. Reach for it when the science is defensible but the clinical-priority argument is what CID rejected. It is fully open access, so budget the article-processing charge (list price $3,090 / £2,490 / €2,690, with country-tiered and waiver options) into the decision.

7. Lancet Infectious Diseases. Reach for this only when the core finding is genuinely practice-changing at a global or public-health scale. The bar is the highest on this list and the volume is small, so it suits work where the clinical or policy consequence, not the dataset, is the protagonist.

The cascade strategy

CID runs an IDSA portfolio transfer route, and a rejecting CID editor can offer a one-click transfer that carries your manuscript files, and your reviewer reports if you consent, to a more suitable IDSA journal, most often Open Forum Infectious Diseases, the Journal of Infectious Diseases, or the Journal of the Pediatric Infectious Diseases Society. The receiving journal may seek additional peer review rather than accepting the prior reports as final.

You can accept the transfer, decline it, or ignore the offer and submit manually elsewhere. A transfer offer is a routing suggestion, not a quality endorsement, so treat the destination as you would any other target.

Practical ladder by rejection reason:

  • Desk-rejected for scope or clinical priority (basic mechanism, in vitro-only, animal-only, narrow audit)? Do not cascade unchanged into a journal that screens the same way. Pick the journal whose scope actually matches the work: the Journal of Infectious Diseases for mechanism, Clinical Microbiology and Infection for diagnostics, the International Journal of Infectious Diseases for epidemiology.
  • Rejected for lower priority but sound clinical science? This is the classic transfer or step-down case.

Open Forum Infectious Diseases is the native next tier, and accepting the IDSA transfer offer here keeps your reviewer history intact. BMC Infectious Diseases is the alternative if you want a sound-science OA home with no general-interest bar.

  • Rejected after review for limited generalizability, a weak clinical-significance claim, or reporting gaps? Fix it before resubmitting anywhere. Every serious clinical-ID venue will raise the same point.

Carry the revised analysis into the transfer or the manual resubmission.

If you decline the transfer and resubmit manually, remember that CID's own format is a starting template, not a universal one. A CID Major Article runs up to 3,500 words of body text with a 200-word structured abstract (Background, Methods, Results, Conclusions) and up to six combined figures and tables, submitted through the journal's Editorial Manager portal at Editorial Manager submission portal. The next journal almost certainly sets different limits, so reformat to its template before you resubmit rather than carrying CID's structure across unchanged.

Common rejection patterns and desk-rejection triggers

In our pre-submission review work with Clinical Infectious Diseases manuscripts, the rejections we see most often cluster into four named patterns. Each is journal-specific and testable against your own manuscript, which is what makes them worth checking before you resubmit anywhere.

The missing clinical-significance claim. Across our Clinical Infectious Diseases pre-submission reviews, the single most common reviewer trigger is a result that never states the clinical decision it would change. A manuscript reports a difference in outcome or a new association but never names the diagnosis, treatment, prevention, or stewardship choice a clinician would make differently because of it.

CID editors are reading for bedside or health-system consequence, so the abstract and introduction must say, in plain terms, what changes. Add one or two sentences that name the practice decision and tie the primary endpoint to it, and a borderline paper often clears the desk. Without it, even a clean dataset reads as a finding in search of an application.

This is testable: read your own abstract and ask whether a clinician could state, in one sentence, what they would do differently.

Single-center data presented as a general recommendation. A second recurring pattern in the CID manuscripts we review is a single-institution retrospective cohort, framed in the discussion as a broad clinical recommendation, with no analysis of external validity. The editorial question at this journal is not "what happened at your hospital?" but "does this generalize to my patients?" Reviewers consistently flag the gap between the population studied and the claim made.

The fix is an honest external-validity paragraph, a sensitivity analysis across subgroups, or a reframing of the contribution as hypothesis-generating rather than practice-defining.

Insufficient power and mismatched statistics. We see manuscripts where the central clinical claim rests on an underpowered sample, with no sample-size justification and a statistical test that does not match the study design, for example an unadjusted comparison where confounding by indication is obvious. A clinical claim needs a defensible sample size, the right adjustment for the design, and effect sizes with confidence intervals rather than bare p-values.

CID editors screen for under-powered, under-adjusted clinical studies early, and reviewers reject when the analysis cannot distinguish the reported effect from chance or confounding. Check that every headline claim has a matched comparator and an analysis appropriate to your data structure.

Incomplete reporting checklists and scope drift toward basic science. The fourth pattern is twofold. First, a clinical manuscript that omits or only gestures at the relevant reporting checklist (CONSORT for trials, STROBE for observational work, PRISMA for reviews) signals a rushed submission and is caught at the desk.

Second, a paper whose true center of gravity is microbiology mechanism, in vitro susceptibility, or animal-model biology wearing a clinical label belongs at the Journal of Infectious Diseases, and CID's desk filter redirects it fast regardless of quality. Read your own methods and ask: is the reporting checklist complete, and is patient-care relevance the actual protagonist, or a wrapper around a basic-science question?

If it is a wrapper, the right move is a different journal, not a resubmission.

Journal fit

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Who each option is best for

Choose Open Forum Infectious Diseases if your science is sound and the rejection was about clinical priority rather than scope or rigor, and you can absorb an open-access APC. It keeps you in the same IDSA family with the lowest scope-mismatch risk and the fastest route.

Choose the Journal of Infectious Diseases if the core contribution is pathogenesis, host immunity, microbial biology, or translational mechanism. This is the journal CID itself redirects basic-leaning work to.

Choose Clinical Microbiology and Infection if the manuscript is fundamentally a diagnostics, antimicrobial-resistance, or clinical-microbiology question rather than a bedside-management study.

Choose the International Journal of Infectious Diseases if the real advance is epidemiology, surveillance, or disease control, especially in lower-resource settings, rather than individual-patient management.

Choose Infection if the work is broad, clinically relevant ID that spans etiology, diagnosis, and treatment with a public-health dimension and does not hinge on a single practice-changing claim.

Choose BMC Infectious Diseases if the science is methodologically sound but the clinical-priority argument is exactly what CID rejected, and you want a fast open-access home judged on rigor, not general interest.

Before you resubmit

Don't just resubmit the same file down the ladder. The fastest way to collect a second rejection is to send an unrevised manuscript to a journal that screens for the same thing CID did, and some manuscripts need real work, not a faster next submission. A desk rejection for scope or clinical priority is a routing problem you can fix by choosing the right journal and reformatting to its template.

A post-review rejection for limited generalizability, a weak clinical-significance claim, or reporting gaps is a substance problem, and the same concerns will reappear at any serious venue. Be honest about which one you got.

Two cases call for real work before resubmitting, not a faster next submission. First, if reviewers questioned whether the result generalizes or whether it changes practice, the manuscript needs the external-validity analysis and the clinical-decision framing it was missing. Second, if the power or statistics were challenged, new analysis, and sometimes new data, is the only fix. Appealing is rarely worth it: a scope or clinical-priority rejection is an editorial judgment, not a factual error, and the appeal queue is slower than a clean resubmission to a better-fit journal.

Resubmission checklist

Before submitting to your next journal, work through these factors. A few hours here saves weeks of waiting on a second rejection.

Factor
Question to answer
Why it matters
Scope and priority fit
Does the new journal's published scope actually cover this work, and at the right priority level?
Scope and priority mismatch is the fastest desk rejection; verify against the journal's own scope, not its title
Clinical-significance claim
Does the abstract name the diagnosis, treatment, prevention, or stewardship decision the result would change?
The most common CID reviewer trigger; the next clinical journal will check too
Generalizability
Have you discussed external validity, or reframed single-center work as hypothesis-generating?
Single-center data framed as general recommendation is a recurring reject reason
Power and statistics
Does every headline claim have a defensible sample size, adjustment, and effect size with confidence intervals?
Under-powered, under-adjusted clinical studies are caught at desk screen across this journal class
Reporting checklist and reformatting
Is the relevant checklist complete (CONSORT, STROBE, PRISMA), and have you adapted to the new journal's template and cover letter?
An incomplete checklist or carried-over formatting signals a rushed cascade

Run a Clinical Infectious Diseases manuscript scope and readiness check to confirm scope alignment, clinical-significance framing, and reporting completeness before you resubmit. You can also find a better-fit alternative journal in 30 seconds before you finalize the target.

Frequently asked questions

Match the next venue to why it was rejected. For sound clinical work that did not clear the priority bar, Open Forum Infectious Diseases (OFID, the IDSA open-access sister title) is the native step down. For pathogenesis, host-immunity, or translational work, the Journal of Infectious Diseases (JID). For diagnostics and clinical microbiology, Clinical Microbiology and Infection (CMI). For global and outbreak epidemiology, the International Journal of Infectious Diseases (IJID). For broad clinical ID with a public-health angle, Infection.

If it was a desk rejection for scope or priority, you can resubmit to a better-fit journal immediately after reformatting. If reviewers questioned generalizability, the clinical-significance claim, or reporting rigor, budget two to four weeks to add that analysis first. Sending the same manuscript down the ladder unchanged usually earns the same critique at the next journal.

Appeals rarely succeed unless you can point to a clear factual error in the editorial assessment. A desk rejection for scope or clinical priority is an editorial judgment, not an error, so targeting a better-fit journal is almost always faster than appealing.

Yes. A rejecting CID editor can offer a transfer to another IDSA journal, most often Open Forum Infectious Diseases, the Journal of Infectious Diseases, or the Journal of the Pediatric Infectious Diseases Society. Your reviewer reports travel with the manuscript if you consent, and the receiving journal may seek additional review. A transfer offer is a routing suggestion, not an obligation.

Rejection is the normal outcome. CID accepts roughly 15 to 20 percent of submissions, and many papers are desk-rejected within about a week, before external review begins. A rejection is information about clinical priority and fit, not a verdict on the science.

References

Sources

  1. Sources used for the journal facts on this page (scope, transfer mechanics, selectivity, and metrics) are the primary Oxford Academic, IDSA, and Clarivate references below, cross-checked against the journals' own guides for authors. Metrics and rejection patterns are kept consistent with our other Clinical Infectious Diseases pages.
  2. Clinical Infectious Diseases - Author Guidelines (Oxford Academic)
  3. Clinical Infectious Diseases - Why Publish (Oxford Academic)
  4. Open Forum Infectious Diseases - About (Oxford Academic)
  5. IDSA Journals (Oxford Academic)
  6. Clarivate Journal Citation Reports (JCR 2024)

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