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Publishing Strategy10 min readUpdated Jul 17, 2026

Rejected from Critical Care? Where to Submit Next

A post-rejection routing guide for Critical Care manuscripts: when to rebuild the ICU-actionability claim, and when to move to Critical Care: Sepsis and Severe Infection, Intensive Care Medicine, AJRCCM, BMJ, BMC Medicine, JAMA Network Open, or a specialist clinical venue.

By Manusights Editorial Team
Editorial processThe Manusights editorial team researches and maintains our Clinical Medicine & Public Health guides, drawing on what we see across thousands of pre-submission manuscript reviews.How we work

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Quick answer: If you were rejected from Critical Care, do not send the same ICU pitch to another clinical journal unchanged. First decide whether the rejection exposed an ICU-actionability problem, methods problem, reporting-checklist problem, ethics or registration problem, data-availability problem, reviewer-routing problem, article-type problem, or transfer-fit problem. If the manuscript still directly improves care for critically ill patients, rebuild the Critical Care package. If the real contribution is respiratory medicine, sepsis, general medicine, emergency medicine, implementation science, critical-care nursing, clinical epidemiology, or translational biology, route the paper around that center of gravity.

Before spending another submission cycle, run a Critical Care rejection-recovery check to decide whether the manuscript needs a Critical Care rebuild, a Critical Care: Sepsis and Severe Infection transfer, an Intensive Care Medicine route, an AJRCCM route, a BMJ route, a BMC Medicine route, a JAMA Network Open route, or a specialist clinical venue.

Use this page after a rejection. For pre-submission fit and requirements, compare the Critical Care submission guide, Critical Care submission process, Critical Care under-review status guide, and Critical Care journal hub. For adjacent local routes, compare BMC Medicine, BMJ, JAMA, JAMA Network Open, and European Respiratory Journal.

Why this rejection needs routing diagnosis

Critical Care is not a general hospital-medicine journal with an ICU keyword. Springer describes it as an international clinical medical journal that aims to improve care for critically ill patients by acquiring, discussing, distributing, and promoting evidence-based information relevant to intensivists.

That aim makes post-rejection routing concrete. A rejected manuscript may still be clinically valid, statistically interesting, and medically important, but not sufficiently actionable for intensivists. The next journal should follow the decision's real signal, not the title prestige of nearby clinical journals.

The paper may still be a Critical Care paper whose abstract, first table, reporting checklist, ethics language, trial registration, data availability, reviewer suggestions, or cover letter needs repair. It may fit Critical Care: Sepsis and Severe Infection if the sepsis or severe-infection contribution is central and a transfer offer matches. It may fit Intensive Care Medicine if the ICU practice claim is strong enough for a society-critical-care audience. It may fit AJRCCM if respiratory failure, ARDS, ventilation, pulmonary critical care, or sleep and respiratory medicine owns the paper. It may fit BMJ, BMC Medicine, or JAMA Network Open if the contribution is broad clinical medicine rather than ICU-specialist practice.

The next submission should follow the reader who can use the finding.

Current Critical Care facts to check before retargeting

Use these facts as routing checks, not as automatic resubmission reasons.

Fact
Current source-backed detail
Why it matters after rejection
Scope center
Springer says Critical Care aims to improve care for critically ill patients with evidence-based information relevant to intensivists
A rejected paper needs an explicit ICU decision or critical-care consequence, not just hospital relevance
Submission route
The current Springer page links to the Springer Nature submission route at https://submission.nature.com/
A resubmission or transfer still needs a clean Springer Nature record
Journal metric
The current Springer page reports a 5-day median submission-to-first-decision metric
Fast rejection can mean editorial screening, not full external review
Visibility metric
The current Springer page reports 14.1M downloads in 2025
A retargeting plan should preserve reader fit, not only chase a faster acceptance path
Publishing model
Critical Care is open access
Funding and waiver planning matters before another submission
APC
Springer lists the current APC as £3,090 / $4,390 / €3,590, with taxes where applicable
A new open-access route should be planned before transfer or resubmission
Peer review model
Springer says Critical Care uses single-anonymous peer review
Reviewer-risk diagnosis matters because reviewers know author names and affiliations
Reviewer count
Springer says typically two or more experts evaluate each manuscript
The next package should make both ICU and methods reviewer routing obvious
Cover letter
Springer asks authors to explain why the manuscript should be published in Critical Care
The cover letter must prove journal fit, not only summarize novelty
Data availability
BMC guidance asks for availability of data and materials, with repository or additional-file detail where applicable
Clinical-data constraints must be explained clearly instead of hidden in vague "available on request" language
Figure-title limit
Springer says figure titles should be max 15 words
Figure repair can matter after rejection when the first visual does not show ICU consequence cleanly
Figure-legend limit
Springer says figure legends should be max 300 words
Long legends should not compensate for unclear design, cohort, effect, uncertainty, or clinical consequence
Transfer context
Springer Nature says transfer offers can provide alternatives, save reformatting, and are not automatic without author input
Transfer is a routing option, not acceptance or evidence repair

Verify the current Springer journal page, submission guidelines, fee page, and submission route before quoting any metric, APC, reviewer, or workflow detail in a cover letter.

Evidence basis

This page was researched from current Springer Critical Care journal, aims-and-scope, submission-guideline, peer-review, transfer, and APC guidance; existing Manusights Critical Care sibling pages; and adjacent Manusights pages for BMC Medicine, BMJ, JAMA, JAMA Network Open, and European Respiratory Journal.

The non-obvious layer is center-of-gravity diagnosis. A rejected Critical Care manuscript may still be a Critical Care paper if the decision exposed a repairable ICU-actionability, reporting, ethics, data, statistics, or cover-letter problem.

It may be a sepsis companion-journal route if severe infection is the true center. It may be Intensive Care Medicine if the ICU practice contribution is stronger than the current package showed. It may be AJRCCM if respiratory and pulmonary critical care owns the paper. It may be BMJ, BMC Medicine, JAMA Network Open, or a general clinical venue if the contribution matters beyond intensivists. It may be an emergency medicine, infectious disease, anesthesia, nursing, implementation, methods, or translational venue if that reviewer community owns the manuscript.

In our review work with Critical Care-targeted manuscripts, the repeated pattern is clinical plausibility without a clear ICU decision. The manuscript may have mortality, ventilation, vasopressor, sepsis, renal replacement, sedation, delirium, ICU length-of-stay, biomarker, machine-learning, or post-ICU outcome data, but the abstract and first table still do not show what an intensivist should do differently.

First diagnose the rejection reason

Rejection signal
What it probably means
Best next move
"Not a priority for Critical Care"
The result is clinically plausible but does not change ICU practice enough for the journal
Retarget to a specialist, general clinical, or methods venue unless actionability can be rebuilt
"Limited clinical relevance"
The ICU population or bedside consequence is not central enough
Reframe around a clinical decision or route to the field that actually owns the paper
"Methodological concerns"
Bias control, confounding, missingness, model validation, subgroup analysis, or sample size does not support the claim
Fix methods before transfer because the same reviewer risk will travel
"Reporting incomplete"
CONSORT, STROBE, PRISMA, ARRIVE, TRIPOD, protocol, registration, ethics, or data availability is underbuilt
Repair the package before choosing the next journal
"Better fit elsewhere"
The paper belongs to respiratory medicine, emergency medicine, infectious disease, general medicine, nursing, implementation, or methods
Choose the next journal by reviewer pool rather than ICU prestige
"Transfer option offered"
Springer Nature thinks another portfolio journal may fit better
Evaluate fit and evidence repair before accepting transfer
"Language or package concern"
Source files, figures, tables, declarations, cover letter, reviewer suggestions, or data files are hard to process
Fix handleability before retargeting

Do not treat rejection as automatic downgrade. Sometimes the best move is a lateral retarget into the journal whose readers actually own the clinical decision.

Named failure patterns to identify before the next submission

Use these labels to turn the decision letter into a repair plan.

ICU-actionability gap: the manuscript reports a credible association, model, intervention, biomarker, or outcome, but the abstract does not explain how it changes care for critically ill patients.

General-medicine drift: the paper is clinically relevant, but the first read sounds like hospital medicine, public health, emergency medicine, respiratory medicine, infectious disease, or health services research rather than intensive care.

Methods-audit gap: the clinical claim depends on observational adjustment, causal inference, prediction modeling, subgroup analysis, trial conduct, missing data, or sensitivity analysis that reviewers cannot audit quickly.

Reporting-integrity gap: the study design needs a checklist, protocol, trial registration, ethics statement, consent language, patient-data boundary, or data-availability statement that is missing or too vague.

Reviewer-routing gap: the paper needs both an intensivist and a methods reviewer, but the title, abstract, cover letter, and suggested reviewers do not make that routing obvious.

Transfer-without-repair gap: authors accept a transfer offer because it is convenient, but the paper still has the same ICU actionability, methods, reporting, or data problem that caused the rejection.

These labels prevent cosmetic retargeting. An ICU-actionability gap is not fixed by adding "critically ill" to the title. A methods-audit gap is not fixed by moving to a less selective journal. A transfer-without-repair gap is not fixed by letting Springer move files.

Best next journals after Critical Care rejection

Next journal or route
Use when the rejection means...
Do not use when...
Rebuild for Critical Care
The manuscript still directly improves care for critically ill patients and the problem is repairable actionability, reporting, methods, or package clarity
The decision identified a different primary clinical audience
Critical Care: Sepsis and Severe Infection
Sepsis, severe infection, host response, antimicrobial strategy, or infection-related ICU care owns the paper and the transfer fit is real
Sepsis is a subgroup or background context rather than the manuscript's center
Intensive Care Medicine
The paper has high-priority ICU practice relevance and can satisfy a specialist critical-care audience
The Critical Care rejection exposed weak actionability or reporting gaps
AJRCCM
Respiratory failure, ARDS, ventilation, pulmonary critical care, or respiratory medicine owns the contribution
The paper is a general ICU workflow, sepsis, or methods paper without respiratory ownership
BMJ
The finding matters to broad clinical practice, policy, or health systems beyond ICU specialists
The manuscript depends on a narrow intensivist reviewer pool
BMC Medicine
The paper has broad biomedical or clinical relevance and open-access fit, but not a specialist ICU-only contribution
The strongest value is a bedside ICU decision
JAMA Network Open
The study is strong, transparent, clinically broad, and open-access aligned
The evidence is incomplete or the contribution is mainly local ICU workflow
Specialist field journal
Emergency medicine, infectious disease, anesthesia, nursing, implementation science, clinical epidemiology, or translational biology owns the reader job
The paper is still trying to be a general critical-care journal paper

The right next venue is the one where the strongest evidence becomes central rather than defensive.

Submit If / Think Twice If

Submit if:

  • the next journal's readers own the clinical decision your manuscript actually informs
  • the title, abstract, first table or figure, methods, reporting checklist, and cover letter point to one reviewer community
  • ethics approval, consent language, registration, data availability, and conflicts are ready before upload
  • the methods section makes bias, confounding, missingness, sample size, subgroup, and sensitivity-analysis limits inspectable
  • APC, institutional agreement, waiver, or funder coverage has been checked for the next open-access route

Think twice if:

  • the new submission is mostly the rejected Critical Care package with a different journal name
  • the manuscript still implies ICU actionability without naming the bedside decision, protocol, monitoring change, or evidence-synthesis consequence
  • the first table reports statistical significance but hides effect size, uncertainty, missingness, or clinical relevance
  • the chosen journal is attractive mainly because it sounds adjacent to Critical Care rather than because its reviewers own the claim
  • a transfer offer is being used to avoid fixing methods, checklist, ethics, data, or cover-letter problems

When to rebuild for Critical Care

Rebuild for Critical Care only if the manuscript still clears the journal's core fit test: it advances care for critically ill patients and gives intensivists evidence they can interpret, debate, or use.

Route back toward Critical Care if:

  • the editor invited a revised submission or the rejection reason is narrow and repairable
  • the abstract can name the critically ill population, clinical question, and actionability boundary honestly
  • the first table or figure can show design, cohort, effect size, uncertainty, and clinical consequence
  • the methods can support confounding control, missing-data handling, sensitivity analysis, subgroup logic, model validation, or trial conduct at the level claimed
  • reporting checklist, ethics approval, consent, trial registration, protocol, data availability, funding, and COI language can be made audit-ready
  • the cover letter can explain why Critical Care is better than Intensive Care Medicine, AJRCCM, BMJ, BMC Medicine, JAMA Network Open, or a specialist clinical venue

Do not rebuild for Critical Care if the real contribution is general hospital epidemiology, respiratory specialty work, local quality improvement, a narrow biomarker association, a machine-learning model without clinical workflow proof, or a translational mechanism that does not yet affect critical-care practice.

When a transfer or companion route is better

The Critical Care journal page currently notes a guaranteed-out-for-peer-review initiative with Critical Care: Sepsis and Severe Infection when the editors feel a manuscript is better suited to that companion journal. Springer Nature's transfer guidance also explains that transfer offers can present suitable alternatives and save reformatting, but a transfer is not automatic and requires author input.

Use a transfer route when the receiving journal matches the manuscript's actual center. A sepsis transfer can be efficient when severe infection, immune response, antimicrobial strategy, source control, organ failure in infection, or sepsis outcomes own the paper. It is not efficient when sepsis is only one subgroup in a broader ICU study.

Before accepting, answer four questions:

  1. Does the receiving journal's reader care more about the paper than Critical Care readers did?
  2. Did the rejection criticize fit, or did it criticize evidence quality?
  3. Can the title, abstract, first figure, limitations, and cover letter be rebuilt for the receiving journal?
  4. Are methods, reporting, ethics, registration, data availability, and reviewer routing already strong enough to survive the next screen?

If the answer to any item is no, repair before transferring.

When Intensive Care Medicine, AJRCCM, BMJ, or BMC Medicine is better

Intensive Care Medicine is cleaner when the manuscript's center is high-priority ICU practice, physiology, organ support, systems of care, or critical-care evidence synthesis. It is not a fix for weak ICU actionability. The same evidence issues that hurt at Critical Care will usually hurt at another specialist ICU journal.

AJRCCM is cleaner when respiratory critical care owns the paper: ARDS, mechanical ventilation, respiratory failure, pulmonary vascular disease, severe respiratory infection, or pulmonary physiology. If the manuscript is an ICU paper that happens to include ventilated patients, the respiratory route may be too narrow.

BMJ is cleaner when the finding has broad clinical, policy, guideline, or health-system implications beyond ICU specialists. Compare BMJ when the practical audience is general clinicians, health systems, or policy readers rather than intensivists.

BMC Medicine is cleaner when the paper has broad biomedical or clinical relevance and open-access fit but does not need an ICU-only audience. Compare BMC Medicine when the contribution sits between critical care, general medicine, infectious disease, epidemiology, or health systems.

JAMA Network Open is cleaner when the study is clinically broad, transparent, and methodologically mature. Compare JAMA Network Open when the evidence can stand in a broad open-access clinical audience. Do not use it to hide a local, underpowered, or weakly actionable ICU study.

What to do in the next 72 hours

Do not rewrite the whole manuscript immediately. Build a retargeting brief first.

Time window
Action
Output
First 24 hours
Separate fit comments from actionability, methods, reporting, ethics, data, and reviewer-routing comments
One-sentence diagnosis: ICU-actionability gap, methods-audit gap, reporting-integrity gap, reviewer-routing gap, transfer-fit gap, or package gap
24 to 48 hours
Choose the destination family before the destination journal
Critical Care repair, sepsis companion route, ICU specialist route, respiratory route, general clinical route, or specialist field route
48 to 72 hours
Rewrite title, abstract, first table or figure, limitations paragraph, methods audit, data statement, reviewer suggestions, and cover letter for that family
A retargeting package rather than a recycled rejected submission

If the paper cannot be classified in 72 hours, pause. That usually means it is trying to be a specialist ICU paper, respiratory paper, general clinical paper, methods paper, and translational paper at once.

Readiness check

Run the scan while the topic is in front of you.

See score, top issues, and journal-fit signals before you submit.

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In our review work with Critical Care manuscripts, these rejection patterns decide the next venue

In our review work with Critical Care-targeted manuscripts, the worst retargeting mistakes happen when authors treat ICU journals, respiratory journals, general medical journals, and open-access clinical journals as interchangeable. We observe the same failure when a rejection is treated as a prestige problem rather than a map of actionability, methods, reporting, data, and reviewer routing. We separate the decision letter into testable patterns before recommending the next journal.

Critical Care actionability pattern: the abstract says the finding is relevant to critically ill patients, but the first table or figure does not show the clinical decision that changes. In this pattern, the paper should not simply move to Intensive Care Medicine or JAMA Network Open. The title, abstract, first table, limitations paragraph, and cover letter must say whether the work changes ventilation, vasopressor use, sepsis management, triage, monitoring, renal support, sedation, delirium prevention, post-ICU follow-up, or evidence synthesis.

Critical Care methods-audit pattern: the manuscript is clinically plausible, but the methods section does not let reviewers audit confounding, missingness, model calibration, sensitivity analysis, subgroup boundaries, trial conduct, or sample size. This pattern should usually be repaired before any transfer. A receiving editor can inherit files and reviewer comments, but the next reviewers still need effect size, uncertainty, bias control, and data availability to be inspectable.

Critical Care reporting-integrity pattern: the rejection may look like journal fit, but the weak point is a missing CONSORT, STROBE, PRISMA, ARRIVE, TRIPOD, protocol, ethics, registration, consent, data-availability, or conflict statement. For Critical Care and adjacent clinical journals, those are not administrative details. They are part of whether the clinical claim can be trusted.

Critical Care reviewer-routing pattern: the manuscript sits between ICU practice, respiratory medicine, sepsis, emergency care, infectious disease, health services research, translational biology, and clinical epidemiology. If the cover letter and suggested reviewers do not identify both the clinical owner and methods owner, the paper can be rejected as unfocused even when the science is real.

The better retargeting move is usually more specific: identify the clinical decision, choose the reviewer pool, rebuild the title and abstract around that decision, then decide whether the next journal's format, APC, transfer path, and reader expectations fit.

Manuscript repair map

If the rejected paper's strongest claim is...
Route first toward...
Retargeting change
Direct improvement to care for critically ill patients
Critical Care repair
Rebuild ICU actionability, first table, reporting checklist, data statement, and cover letter
Sepsis or severe infection in ICU
Critical Care: Sepsis and Severe Infection or infection/ICU specialist route
Center infection phenotype, organ failure, antimicrobial strategy, and sepsis-specific outcome
High-priority specialist ICU practice
Intensive Care Medicine or ICU society journal
Center ICU practice relevance and specialist reviewer expectations
Respiratory failure, ARDS, ventilation, pulmonary critical care
AJRCCM or respiratory-critical-care route
Center respiratory physiology, ventilation strategy, pulmonary outcome, and respiratory audience
Broad clinical or health-system consequence
BMJ, BMC Medicine, JAMA Network Open, or general clinical route
Center generalizable clinical decision, policy, or evidence-synthesis value
Emergency medicine, anesthesia, nursing, implementation, methods, or translational biology
Specialist field journal
Center the reviewer community that owns the actual mechanism or use case

Resubmission or retargeting checklist

Before the next submission, confirm:

  • the rejection reason is summarized in one sentence
  • the next journal is chosen by manuscript center of gravity
  • the title no longer overclaims Critical Care-level ICU actionability if the route changed
  • the abstract names the actual critically ill population, clinical question, method, and decision consequence
  • the first table or figure shows effect size, uncertainty, missingness, and clinical consequence
  • methods support confounding control, sample size, model validation, subgroup logic, and sensitivity analysis where relevant
  • checklist, protocol, ethics approval, consent, trial registration, COI, funding, and data availability are complete
  • the limitations paragraph separates demonstrated clinical implication from inferred practice change
  • reviewer suggestions cover both clinical critical care and the needed methods expertise
  • any Springer Nature transfer offer has been evaluated against fit, evidence repair, package auditability, APC/funding, and timing

If any item fails, fix the package before moving the manuscript. If you want a faster second opinion, run an evidence-strength and journal-fit check before choosing the next destination.

Frequently asked questions

First diagnose whether the rejection was about ICU actionability, study design, reporting completeness, ethics or registration, statistical robustness, reviewer routing, or article type. If the paper still directly improves care for critically ill patients, rebuild for Critical Care or a close ICU venue. If the center is respiratory medicine, sepsis, general medicine, emergency medicine, implementation science, nursing, or methods, choose that reviewer pool instead.

Only consider resubmission if the editor invited it or the rejection reason is narrow and repairable. A serious resubmission should rebuild the title, abstract, first table or figure, methods, reporting checklist, ethics or registration language, data availability, reviewer suggestions, and cover letter together.

Consider a transfer if the receiving journal matches the manuscript's real center of gravity. Springer Nature transfer can save reformatting and move files or reviewer comments, but the author still chooses whether to transfer and the receiving journal still assesses the paper.

Intensive Care Medicine can be better when the manuscript has high-priority ICU evidence, strong practice relevance, and a European or society-critical-care audience. It is not a solution if the Critical Care rejection exposed weak actionability, incomplete reporting, or fragile methods.

Those routes can be better when the paper has broad clinical or health-system relevance beyond ICU specialists. They are weaker choices when the manuscript's value depends on a specialist intensivist reviewer pool.

References

Sources

  1. Critical Care journal page, Springer
  2. Critical Care aims and scope, Springer
  3. Critical Care submission guidelines, Springer

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