Is Cell Host & Microbe a Good Journal? Impact Factor, Comparison, and Fit Verdict
Cell Host & Microbe fit verdict with key metrics, comparison to Nature Microbiology and Immunity, and practical guidance for host-pathogen and microbiome researchers.
Associate Professor, Immunology & Infectious Disease
Author context
Specializes in manuscript preparation and peer review strategy for immunology and infectious disease research, with 10+ years evaluating submissions to top-tier journals.
Journal fit
See whether this paper looks realistic for Cell Host & Microbe.
Run the Free Readiness Scan with Cell Host & Microbe as your target journal and see whether this paper looks like a realistic submission.
Cell Host & Microbe at a glance
Key metrics to place the journal before deciding whether it fits your manuscript and career goals.
What makes this journal worth targeting
- IF 18.7 puts Cell Host & Microbe in a visible tier — citations from papers here carry real weight.
- Scope specificity matters more than impact factor for most manuscript decisions.
- Acceptance rate of ~~12% means fit determines most outcomes.
When to look elsewhere
- When your paper sits at the edge of the journal's stated scope — borderline fit rarely improves after submission.
- If timeline matters: Cell Host & Microbe takes ~30-45 days. A faster-turnaround journal may suit a grant or job deadline better.
- If open access is required by your funder, verify the journal's OA agreements before submitting.
How to read Cell Host & Microbe as a target
This page should help you decide whether Cell Host & Microbe belongs on the shortlist, not just whether it sounds impressive.
Question | Quick read |
|---|---|
Best for | Cell Host & Microbe published by Cell Press is a leading journal for host-pathogen interaction research.. |
Editors prioritize | Novel pathogen mechanism or immune response advancing infection understanding |
Think twice if | Pathogen characterization without host interaction or immune context |
Typical article types | Research Article |
Cell Host & Microbe (IF 18.7, Cell Press) publishes research where the host-pathogen or host-microbiome interface is the central biology. The word "interface" is doing real work here. If the paper is mostly about the pathogen, or mostly about the immune response, or mostly a microbiome catalog, the interaction logic is too thin for this journal.
Key Metrics
Metric | Value |
|---|---|
Impact Factor (2024 JCR) | 18.7 |
Publisher | Cell Press (Elsevier) |
Acceptance Rate | ~5-8% |
Desk Rejection Rate | ~60-70% |
Open Access | Hybrid (subscription with OA option) |
Quartile | Q1 (Microbiology; Immunology) |
What Makes Cell Host & Microbe Different
The journal's identity is built on one editorial principle: both sides of the interaction must matter. This sounds obvious, but it is the source of most desk rejections. A technically excellent virology paper where the host is just a growth substrate gets rejected. A strong immunology paper where the pathogen could be swapped for any other stimulus gets rejected. The interaction itself has to change what the field understands.
This means the strongest Cell Host & Microbe papers typically show how a pathogen reshapes host biology in a way that reveals something new about disease, immunity, or colonization, or how host defense mechanisms alter microbial behavior in ways that matter for infection outcome.
Microbiome papers face an even tighter filter. Descriptive 16S or metagenomic surveys rarely survive the desk screen. The journal wants causal, mechanistic microbiome work with physiological or therapeutic consequence.
How Cell Host & Microbe Compares
Journal | IF (2024) | Best For | Key Difference from Cell Host & Microbe |
|---|---|---|---|
Nature Microbiology | 19.4 | High-impact microbiology, broad | Broader scope, less interaction-focused |
Cell | 42.5 | Flagship biology across all fields | Consequence must transcend infection biology entirely |
Immunity | 26.3 | Immune mechanisms broadly | Immune biology first, pathogen context secondary |
mBio | 5.0 | Broad microbiology (ASM) | Lower bar, broader scope, faster decisions |
Cell Host & Microbe vs Nature Microbiology: Nature Microbiology (IF 18.3) publishes strong microbiology across a wider scope without requiring the same depth of host-microbe interaction. If the paper is primarily about microbial biology with host context added, Nature Microbiology is often the more natural fit.
Cell Host & Microbe vs Cell: Cell can work for infection papers whose consequence reaches far beyond infection biology into general biological principles. This is rare. Most outstanding infection papers belong in Cell Host & Microbe because the audience that cares most sits at the host-microbe interface.
Cell Host & Microbe vs Immunity: Immunity (IF 26.3) publishes broad immune mechanisms. If the strongest story is an immune discovery where the pathogen mainly serves as a tool to reveal it, Immunity is the better target. Choose Cell Host & Microbe when the interaction is the point, not the context.
Cell Host & Microbe vs mBio: mBio (IF 5.0, ASM) is broader and faster with a lower bar. If the paper is strong microbiology but the interaction component is not deep enough for Cell Press, mBio is a realistic and respectable option.
The Editorial Distinction
Cell Host & Microbe editors are in-house Cell Press professionals with infection biology expertise. They are not routing papers to external academic editors for triage. The desk screen is fast, informed, and focused on one question: does the interaction itself advance what the field understands?
The Cell Press negotiated revision model applies here. Editors will discuss what additional experiments would strengthen the interaction logic, which often means requesting both host-side and microbe-side validation that many authors have not planned for.
Submit If
- Both the host biology and the microbial biology are mechanistically developed in the paper
- The interaction itself is the core contribution, not background or context
- The work includes physiological or in vivo grounding that makes the biology credible beyond cell culture
- The result matters to readers across infection biology, immunity, and microbiome research
- You can handle a negotiated revision that may require experiments on both sides of the interface
Journal fit
See whether this paper looks realistic for Cell Host & Microbe.
Run the scan with Cell Host & Microbe as the target. Get a manuscript-specific fit signal before you commit.
Think Twice If
- The paper is mainly pathogen characterization with thin host context
- The immunology is strong but the microbial side is generic or interchangeable
- The microbiome data is rich but the mechanism remains correlative
- The work is technically strong but the audience is one specialist organism community
- Immunity or Nature Microbiology would frame the contribution more honestly
Frequently Asked Questions
Is Cell Host & Microbe a good journal?
Yes. Cell Host & Microbe is a top-tier Cell Press journal with a 2024 impact factor of 18.7 and Q1 ranking in Microbiology and Immunology. It publishes mechanistic research on host-pathogen interactions, microbiome biology, and infection where both sides of the interface do real scientific work.
What is Cell Host & Microbe's acceptance rate?
Cell Host & Microbe accepts approximately 5-8% of submissions. The journal requires that both the host biology and the microbial biology are mechanistically developed and that the interaction itself is the core contribution.
Is Cell Host & Microbe peer reviewed?
Yes. Cell Host & Microbe uses rigorous peer review managed by professional in-house Cell Press editors with deep expertise in infection biology and host defense. Revisions follow the Cell Press negotiated model.
What is Cell Host & Microbe's impact factor?
Cell Host & Microbe has a 2024 JCR impact factor of 18.7. It is ranked Q1 in both Microbiology and Immunology, making it the top venue for host-microbe interaction research.
Bottom Line
Cell Host & Microbe is the right journal when the host-microbe interaction is the discovery, not the setup. It is the wrong journal when one side of the interface is doing all the scientific work and the other side is just along for the ride.
Before submitting, a Cell Host & Microbe scope and readiness check can assess whether your interaction logic is strong enough for Cell Press editorial triage.
Before you submit
A Cell Host & Microbe submission readiness check identifies the specific framing and scope issues that trigger desk rejection before you submit.
Frequently asked questions
Yes. Cell Host & Microbe is a top-tier Cell Press journal with a 2024 impact factor of 18.7 and Q1 ranking in Microbiology and Immunology. It publishes mechanistic research on host-pathogen interactions, microbiome biology, and infection where both sides of the interface do real scientific work.
Cell Host & Microbe accepts approximately 5-8% of submissions. The journal requires that both the host biology and the microbial biology are mechanistically developed and that the interaction itself is the core contribution.
Yes. Cell Host & Microbe uses rigorous peer review managed by professional in-house Cell Press editors with deep expertise in infection biology and host defense. Revisions follow the Cell Press negotiated model.
Cell Host & Microbe has a 2024 JCR impact factor of 18.7. It is ranked Q1 in both Microbiology and Immunology, making it the top venue for host-microbe interaction research.
Sources
- 1. Cell Host & Microbe journal homepage, Cell Press.
- 2. Cell Host & Microbe information for authors, Cell Press.
- 3. Clarivate Journal Citation Reports (released June 2025).
Final step
See whether this paper fits Cell Host & Microbe.
Run the Free Readiness Scan with Cell Host & Microbe as your target journal and get a manuscript-specific fit signal before you commit.
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Where to go next
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Same journal, next question
- Cell Host and Microbe Submission Guide
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- Cell Host & Microbe Acceptance Rate: What Authors Can Use
- Cell Host & Microbe Impact Factor 2026: Ranking, Quartile & What It Means
- Cell Host & Microbe APC and Open Access: Current Cell Press Pricing, Agreement Coverage, and Real Tradeoffs
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