Journal Guides8 min readUpdated Mar 17, 2026

Nature Neuroscience 'Under Consideration': Status Meanings and Timeline

If your Nature Neuroscience submission shows Under Consideration, here is what each status means, the timeline, and what passing the desk signals.

Research Scientist, Neuroscience & Cell Biology

Author context

Works across neuroscience and cell biology, with direct expertise in preparing manuscripts for PNAS, Nature Neuroscience, Neuron, eLife, and Nature Communications.

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Decision cue: Nature Neuroscience desk rejects 70 to 80% of submissions. If your paper shows "Under Consideration" past the 10-day mark, you have very likely survived the desk screen. The journal publishes neuroscience research that advances conceptual understanding of the brain, not just incremental observations. If you are past the desk, the editor believes your result could change how the field thinks about a neural process or system.

Check your next neuroscience submission's readiness while you wait.

Nature Neuroscience review pipeline

Status
What is happening
Typical duration
Received
Administrative processing
1 to 2 days
Under Consideration
Editor evaluating, consulting team, possibly inviting reviewers
Days to weeks
Under Review (if shown)
Sent to external reviewers
4 to 8 weeks
Decision in Process
Editor reviewing reports
3 to 7 days
Decision Made
Check email
Same day

What Nature Neuroscience editors screen for

  • Conceptual advance in neuroscience: Does this change how we think about a neural process? A new dataset or observation without conceptual insight is insufficient.
  • Multi-level evidence: From molecules to circuits to behavior. The strongest papers connect across levels of analysis.
  • Methodological rigor: Given the field's reproducibility concerns (see Pre-Submission Review for Neuroscience), methods and statistical approaches face heightened scrutiny.
  • Sample sizes and statistical power: The median neuroimaging study has n=25, but brain-behavior associations may require thousands. Editors check whether the sample is adequate for the claims.

What happens during peer review

Papers that pass the desk screen go to 2 to 3 expert reviewers. Nature Neuroscience reviewers are selected for both their technical expertise and their ability to evaluate the conceptual significance of the work. The review evaluates:

  • whether the finding changes understanding of a neural process or system
  • whether the evidence is multi-level (molecular, circuit, systems, behavior)
  • whether the methodology is rigorous enough for the claims
  • whether the sample sizes and statistical approaches are appropriate (given the field's reproducibility concerns)
  • whether the manuscript is accessible to a broad neuroscience audience

Understanding the decision

  • Revise: the most common outcome for papers that pass review at Nature journals. Revisions typically require new experiments that address mechanistic questions. The revision period may be months, not weeks.
  • Reject after review: the conceptual advance or evidence strength did not meet the threshold. The reviewer feedback is often detailed and constructive even in rejection.
  • Redirect: the editor may suggest Nature Communications, Nature Methods, or a specialty neuroscience journal where the work has better scope fit.

When to worry, when to wait

Situation
What it likely means
Under Consideration, day 5
Editor reading or discussing
Under Consideration, day 10+
Likely passed desk, reviewers being invited
Under Consideration, day 45+
Possible reviewer delay. Follow up politely
Decision in Process
Reports received, decision within days

What to do while waiting

  • do not submit the same paper elsewhere
  • prepare for reviewer requests for additional electrophysiology, behavioral, or imaging experiments
  • Nature Neuroscience revisions often require new experiments that address mechanistic questions
  • check your next manuscript's readiness while you wait
References

Sources

  1. Nature Neuroscience submission guidelines
  2. Nature Neuroscience editorial process
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