Journal Guides6 min readUpdated Apr 21, 2026

Science Immunology Impact Factor

Science impact factor is 45.8. See the current rank, quartile, and what the number actually means before you submit.

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Specializes in manuscript preparation and peer review strategy for oncology and cell biology, with deep experience evaluating submissions to Nature Medicine, JCO, Cancer Cell, and Cell-family journals.

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Metric context

A fuller snapshot for authors

Use Science's impact factor as one signal, then stack it against selectivity, editorial speed, and the journal guide before you decide where to submit.

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Impact factor45.8Current JIF
Acceptance rate<7%Overall selectivity
First decision~14 days to first decisionProcess speed

What this metric helps you decide

  • Whether Science has the citation profile you want for this paper.
  • How the journal compares to nearby options when prestige or visibility matters.
  • Whether the citation upside is worth the likely selectivity and process tradeoffs.

What you still need besides JIF

  • Scope fit and article-type fit, which matter more than a high number.
  • Desk-rejection risk, which impact factor does not predict.
  • Timeline and cost context.
Submission context

How authors actually use Science's impact factor

Use the number to place the journal in the right tier, then check the harder filters: scope fit, selectivity, and editorial speed.

Use this page to answer

  • Is Science actually above your next-best alternatives, or just more famous?
  • Does the prestige upside justify the likely cost, delay, and selectivity?
  • Should this journal stay on the shortlist before you invest in submission prep?

Check next

  • Acceptance rate: <7%. High JIF does not tell you how hard triage will be.
  • First decision: ~14 days to first decision. Timeline matters if you are under a grant, job, or revision clock.
  • Publishing cost and article type, since those constraints can override prestige.

Quick answer: Science Immunology has a 2024 JCR impact factor of 16.3, a five-year JIF of 17.7, and a Q1 rank of 6/183 in Immunology. The practical read is that this is a top-tier immunology journal with a Science-family screen for breadth, mechanism, and consequence, not just technical competence.

Science Immunology impact factor at a glance

Metric
Value
Impact Factor
16.3
5-Year JIF
17.7
JCI
3.81
Quartile
Q1
Category Rank
6/183
Total Cites
13,743
Citable Items
131
Cited Half-Life
3.7 years
Scopus Impact Score 2024
13.14
SJR 2024
8.22
h-index
123
Publisher
AAAS
ISSN
2470-9468

That places Science Immunology in roughly the top 3% of its JCR category by current rank.

What 16.3 actually tells you

The headline number is high, but the more useful signal is the full profile. A 16.3 JIF, 17.7 five-year JIF, and 3.81 JCI together tell you the journal is not living on brand alone. Its papers are performing strongly even after field normalization.

This also fits the journal's editorial identity. AAAS describes Science Immunology as a monthly, online-only, peer-reviewed journal designed to advance understanding of the immune system by showcasing innovative advances from studies in all organisms and model systems, including humans.

That is a broad mandate, but not a permissive one. The number reflects a journal that expects work to travel beyond one immunology niche.

Science Immunology impact factor trend

The JCR row above is the authoritative impact factor on this page. For the longer directional view, the table below uses the open Scopus-based impact score series as a trend proxy.

Year
Scopus impact score
2016
0.00
2017
5.95
2018
8.16
2019
9.03
2020
11.03
2021
22.48
2022
19.83
2023
14.04
2024
13.14

Directionally, the open citation signal is down from 14.04 in 2023 to 13.14 in 2024, and well below the 2021 peak. That is not surprising. Science Immunology benefited from a stronger citation cycle when immunology broadly, and infection and inflammation research in particular, were receiving exceptional attention.

The better interpretation is that the journal normalized while still remaining elite. The current JCR row and category rank say it is still firmly in the top immunology tier.

Why the number can mislead authors

The mistake is to read a Science-family immunology journal as if it were simply a better-branded specialist venue.

That is usually where authors get into trouble. Science Immunology tends to reward papers with:

  • clear broad immunology consequence
  • mechanism that feels decisive, not just suggestive
  • importance visible outside one technical subcommunity
  • a manuscript that reads like an event for immunologists, not only for specialists

A strong paper can still be too incremental for this level.

How Science Immunology compares with nearby choices

Journal
Best fit
When it beats Science Immunology
When Science Immunology is stronger
Science Immunology
Broad immunology advances with strong consequence
When the paper has field-wide value and deserves a high-end general immunology screen
When the story travels beyond one niche but is still more immunology-specific than general-science
Immunity
High-end mechanistic immunology
When the paper is a better Cell Press-style mechanistic fit
When the work feels more like a broad immunology advance in the AAAS lane
Nature Immunology
Top-end immunology with flagship consequence
When the paper is even broader or sharper at the very top end
When the Science Immunology editorial fit is cleaner
Journal of Experimental Medicine
High-trust mechanistic and disease immunology
When the paper is stronger as a disease-mechanism story than a flagship broad immunology event
When the result has broader immunology consequence across subfields

That is why a manuscript can be excellent and still be below Science Immunology's threshold. The issue is usually breadth of consequence, not competence.

In our pre-submission review work

In our pre-submission review work on manuscripts targeting Science Immunology, the most common failure is overframing. The data are good, sometimes very good, but the manuscript is written as if one technically strong result automatically becomes a high-end broad immunology paper.

Editors usually test that claim immediately.

What pre-submission reviews reveal about Science Immunology submissions

In our pre-submission review work on manuscripts targeting Science Immunology, four failure patterns recur.

The advance is real but too narrow. This is common with beautifully executed work whose importance is obvious mainly to one specialist readership.

Phenotyping outruns mechanism. The biology looks interesting, but the manuscript does not yet explain enough about why the immune phenomenon happens.

The significance claim is broader than the evidence. Authors often write the paper as a field-wide advance before the data actually support that reach.

The story is technically strong but not conceptually clean enough. Science Immunology usually rewards papers where the central immunology message is simple, sharp, and hard to miss.

If that sounds familiar, a Science Immunology submission readiness check is usually more useful than another line-edit pass.

How to use this number in journal selection

Use the impact factor to place Science Immunology correctly. It is a top-tier immunology target, and the JCI confirms it is performing at that level.

But do not let the number make the decision for you. The better question is whether the manuscript changes how a broad immunology readership thinks, not whether it is just the best version of a niche story.

What the number does not tell you

The impact factor does not tell you whether the paper is broad enough, conceptually sharp enough, or mechanistically closed enough for a Science-family editorial screen. It also does not tell you whether a different high-end immunology journal would be the more honest first target.

That is where many good papers miss. The metric can place the journal. It cannot certify that the manuscript is operating at the journal's level.

Submit if / Think twice if

Submit if:

  • the paper has broad immunology consequence
  • the mechanism is strong enough to support the scale of the claim
  • the importance is visible outside one narrow subcommunity
  • the manuscript reads like a clear conceptual advance

Think twice if:

  • the result is mainly niche-specific
  • phenotyping is strong but mechanistic closure is thin
  • the title and framing overstate the field-wide consequence
  • another high-end immunology journal would fit the story more honestly

Bottom line

Science Immunology has an impact factor of 16.3 and a five-year JIF of 17.7. The stronger signal is its combination of elite rank, high normalized influence, and a Science-family filter for broad immunology consequence.

If the paper is not clearly bigger than a specialist story, the metric will flatter the fit.

Frequently asked questions

Science Immunology has a 2024 JCR impact factor of 16.3, with a five-year JIF of 17.7. It is Q1 and ranks 6th out of 183 journals in Immunology.

Yes. It sits in the top tier of immunology publishing. The stronger signal is the combination of a 16.3 JIF, high JCI of 3.81, and a Science-family editorial bar for broad immunology consequence.

The open Scopus-based impact score peaked during a stronger citation cycle and then normalized. The current JCR row still places the journal comfortably in the top immunology tier.

No. The journal still expects broad immunology consequence, clear mechanism, and importance beyond one narrow subcommunity. Strong specialist work can still be the wrong fit.

The common misses are incremental immunology framed as a flagship advance, phenotyping without enough mechanistic closure, and papers whose importance is legible only inside one technical niche.

References

Sources

  1. Clarivate Journal Citation Reports (JCR 2024 data used for the page)
  2. AAAS launch note for Science Immunology
  3. AAAS 2026 Science media kit
  4. Science Immunology journal homepage
  5. Resurchify: Science Immunology (used for the Scopus impact-score trend and SJR context)

Reference library

Use the core publishing datasets alongside this guide

This article answers one part of the publishing decision. The reference library covers the recurring questions that usually come next: whether the package is ready, what drives desk rejection, how journals compare, and what the submission requirements look like across journals.

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