Journal Guides7 min readUpdated Mar 21, 2026

Circulation Acceptance Rate

Circulation acceptance rate is about 12%. Use it as a selectivity signal, then sanity-check scope, editorial fit, and submission timing.

Assistant Professor, Cardiovascular & Metabolic Disease

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Works across cardiovascular biology and metabolic disease, with expertise in navigating high-impact journal submission requirements for Circulation, JACC, and European Heart Journal.

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Circulation accepts approximately 10-12% of submissions. That's more permissive than NEJM or the Lancet but still highly selective for a cardiovascular journal. The desk rejection rate runs 70%+, and the papers that get through are almost always clinical or translational work with clear relevance to how cardiologists treat patients.

Quick answer

Circulation's overall acceptance rate is roughly 10-12%. Desk rejection accounts for 70%+ of submissions. Papers entering peer review have an estimated 35-45% acceptance rate. The editorial filter centers on whether the finding changes cardiovascular clinical practice or translational understanding. Basic cardiovascular biology without clinical connection is usually redirected to Circulation Research.

The selectivity breakdown

Metric
Value
Overall acceptance rate
~10-12%
Estimated desk rejection rate
70%+
Post-review acceptance rate
~35-45% (estimated)
Impact Factor (2024 JCR)
38.6
Annual publications
~400 original research articles
Time to desk decision
1-3 weeks

Where papers get filtered

The desk: clinical vs. basic science

The fastest desk rejections happen when a paper is fundamentally basic cardiovascular science. A study of cardiac ion channel regulation at the molecular level, without any clinical bridge, belongs at Circulation Research (IF 16.5), not Circulation. The editors make this distinction quickly.

Papers that survive the desk typically answer "yes" to: would a practicing cardiologist read this and consider changing something about how they treat patients?

That doesn't mean the paper has to be a clinical trial. Translational work counts. But the translational bridge needs to be visible, not theoretical.

Peer review: evidence strength

Among papers that enter review, rejection usually comes from:

  • The clinical endpoints aren't strong enough (surrogate markers instead of hard outcomes)
  • The study design has limitations that undermine the clinical conclusion
  • The population is too narrow for Circulation's broad cardiovascular readership
  • The finding replicates what's already known without adding a meaningful new dimension

The AHA family redirect

Circulation sits atop the AHA journal family. When editors see merit but not flagship-level importance, they often offer to transfer to Circulation: Heart Failure, Circulation: Arrhythmia, or another specialty title. These are respected journals in their own right (IFs 9-25), and the transfer typically comes with the editor's recommendation.

Taking the transfer seriously is often the right move. A paper that's borderline for Circulation may be a strong acceptance at a specialty title.

How Circulation compares

Journal
Acceptance Rate
What it selects for
Circulation
~10-12%
Clinical and translational cardiovascular impact
European Heart Journal
~15%
Broad European cardiovascular research
JACC
~10%
Clinical cardiology with ACC focus
Circulation Research
~15%
Basic cardiovascular biology
NEJM
~5%
Practice-changing evidence across all medicine

Circulation vs. European Heart Journal is the comparison most cardiologists face. EHJ has a slightly higher acceptance rate and a European editorial perspective. Circulation has an American (AHA) orientation. The scope overlap is substantial, and many papers could go to either.

Should you submit?

Submit if:

  • the finding changes how cardiologists understand or treat cardiovascular disease
  • the evidence is clinical or has a clear translational bridge to patient care
  • the study population and endpoints are broad enough for the AHA's flagship readership
  • you're comfortable with the AHA family cascade if the paper doesn't clear the flagship

Think twice if:

  • the paper is primarily basic cardiovascular biology (Circulation Research is the better target)
  • the finding is specific to one cardiovascular subspecialty (a Circulation specialty title may fit better)
  • European Heart Journal or JACC would reach your target audience more effectively
  • the clinical implications are speculative rather than evidence-supported

A free manuscript scan can help assess whether the cardiovascular framing meets Circulation's clinical threshold before you submit.

FAQ

What is the Circulation acceptance rate?

Approximately 10-12%. Most rejections happen at the desk (70%+).

How hard is it to publish in Circulation?

Selective but not impossible. The key filter is clinical relevance. Basic cardiovascular science belongs at Circulation Research. Clinical and translational work with clear patient-care implications has the best chance.

Does Circulation transfer papers to specialty journals?

Yes. The AHA journal family includes Circulation: Heart Failure, Circulation: Arrhythmia and Electrophysiology, and others. Editors often offer transfers for papers with cardiovascular merit below the flagship threshold.

What's the difference between Circulation and JACC?

Circulation is AHA-affiliated. JACC is ACC-affiliated. The scope overlaps substantially. Circulation emphasizes cardiovascular science broadly; JACC emphasizes clinical cardiology practice.

References

Sources

  1. Clarivate Journal Citation Reports (released June 2025)
  2. Circulation information for authors

Reference library

Use the core publishing datasets alongside this guide

This article answers one part of the publishing decision. The reference library covers the recurring questions that usually come next: how selective journals are, how long review takes, and what the submission requirements look like across journals.

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