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JBC Impact Factor

Journal of Biological Chemistry impact factor is 4.1. See the current rank, quartile, and what the number actually means before you submit.

Editorial processThe Manusights editorial team researches and maintains these guides using source review, field-specific analysis, and our documented editorial process.How we work

Journal evaluation

Want the full picture on Journal of Biological Chemistry?

See scope, selectivity, submission context, and what editors actually want before you decide whether Journal of Biological Chemistry is realistic.

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Metric context

A fuller snapshot for authors

Use Journal of Biological Chemistry's impact factor as one signal, then stack it against selectivity, editorial speed, and the journal guide before you decide where to submit.

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What this metric helps you decide

  • Whether Journal of Biological Chemistry has the citation profile you want for this paper.
  • How the journal compares to nearby options when prestige or visibility matters.
  • Whether the citation upside is worth the likely selectivity and process tradeoffs.

What you still need besides JIF

  • Scope fit and article-type fit, which matter more than a high number.
  • Desk-rejection risk, which impact factor does not predict.
  • Timeline and cost context.

Five-year impact factor: 4.3. These longer-window metrics help show whether the journal's citation performance is stable beyond a single JIF snapshot.

Submission context

How authors actually use Journal of Biological Chemistry's impact factor

Use the number to place the journal in the right tier, then check the harder filters: scope fit, selectivity, and editorial speed.

Use this page to answer

  • Is Journal of Biological Chemistry actually above your next-best alternatives, or just more famous?
  • Does the prestige upside justify the likely cost, delay, and selectivity?
  • Should this journal stay on the shortlist before you invest in submission prep?

Check next

  • Acceptance rate and desk-rejection risk, because impact factor does not tell you if the journal is realistic.
  • First decision: ~8-12 weeks. Timeline matters if you are under a grant, job, or revision clock.
  • Publishing cost and article type, since those constraints can override prestige.

Acceptance-rate source check (October 21, 2026): We have not verified a current acceptance rate for Journal of Biological Chemistry. Check Elsevier’s journal catalog for the publisher’s current figure; an unverified figure does not mean the publisher reports none. Elsevier journal catalog.

Quick answer: The JBC impact factor is 4.1 in the 2026 JCR release, Q2 in Biochemistry & Molecular Biology. That is the Journal of Biological Chemistry (J Biol Chem), the ASBMB flagship founded in 1905. Read the metric alongside the journal's current scope and the contribution your manuscript makes.

ASBMB lists 4.1 as the 2025 Journal Impact Factor on its JBC metrics page (checked 19 October 2026).

Match your manuscript to JBC

Use 4.1 as citation context, then assess the work itself. ASBMB's May 2026 scope announcement retains molecular and biochemical insight while welcoming conceptual advances, foundations for future mechanistic work, and enabling methods or resources. Full mechanistic resolution is not a universal submission requirement. The routing judgments below interpret that scope; they do not predict acceptance.

Your manuscript
What to check for JBC
Mechanism shown with reconstitution, kinetics or structure-activity data
Consider JBC when the evidence supports a substantive molecular insight
A conceptual advance or a foundation for mechanistic work
Potential fit under the expanded scope; explain the biological insight and remaining limits
An enabling method or resource
Show its value for molecular or biochemical research and validate what it enables
A cellular phenotype or another variant of a known enzyme
Test whether it adds a clear conceptual or biochemical contribution; the result's label alone does not decide fit

At a glance

Metric
Value
Impact Factor
4.1
5-Year JIF
4.3
Quartile
Q2
Publisher
American Society for Biochemistry and Molecular Biology
Acceptance rate
Not verified; see publisher catalog
h-index
578
Total Cites (2025)
277,700
ISSN
0021-9258
Founded
1905
Open Access
Fully OA since 2021
APC
~$2,000-$2,500

Data sourced from our analysis of 20,449 journals in the Clarivate 2026 JCR release database.

What 4.1 means for biochemists

JBC's IF (4.1) is lower than Molecular Cell (16) or EMBO Journal (8.4), but the comparison is misleading. JBC publishes ~2,500 papers per year across all of biochemistry. Molecular Cell publishes ~200 highly selective papers. JBC's strength is its breadth and accessibility.

The five-year JIF (4.3) running above the two-year (4.1) shows JBC papers have lasting citation value. Biochemistry is a field where detailed mechanistic studies get cited as reference points for years.

For career purposes, JBC is universally recognized in biochemistry. It's not a prestige journal like Cell or Nature, but a strong JBC paper demonstrates rigorous biochemistry in the field's community journal.

JBC impact factor trend: how to compare years

ASBMB's current snapshot establishes a 2025 JIF of 4.1. It does not, by itself, establish a twenty-year trend or explain why an earlier value changed. Before drawing a career or submission conclusion from a change:

  • Match the metric year, not just the year a report was released.
  • Compare the same measure: a two-year JIF is different from a five-year JIF or CiteScore.
  • Check each earlier value in the corresponding publisher or JCR record before describing a rise, fall, or record low.

ASBMB also reports an h-index of 578 and 277,700 total citations for 2025 in its current snapshot. These describe different aspects of citation history and should not be treated as substitutes for the two-year JIF.

How JBC compares

Journal
IF
What it selects for
JBC
4.1
Rigorous biochemistry broadly
Molecular Cell
16
Deep mechanistic cell biology
EMBO Journal
8.4
European molecular biology
Nucleic Acids Research
15
Nucleic acid research + databases
Biochemistry (ACS)
2.9
ACS biochemistry

Review Timeline

Stage
Typical Duration
First decision
~30 days
Peer review
3-4 weeks
Number of reviewers
2-3
Publication after acceptance
2-3 months
Revision turnaround
2 months requested

JBC is known for relatively fast turnaround. The first editorial decision typically arrives within 30 days, which is faster than many comparable journals. If revisions are requested, the journal gives authors about 2 months to resubmit. Total time from submission to online publication is usually 4-6 months, which is competitive for the field.

Article Processing Charges

JBC has been fully open access since January 2021. All published articles are freely available without a subscription. The APC is approximately $2,000-$2,500, which is lower than many comparable OA journals (for example, Nature Communications charges ~$7,350). ASBMB members receive a discount on the APC. The OA transition has increased JBC's discoverability and download rates, even as the IF has declined.

Readiness check

See how your manuscript scores against Journal of Biological Chemistry before you submit.

Run the scan with Journal of Biological Chemistry as your target journal. Get a fit signal alongside the IF context.

Check my manuscript fitPrivate API processing. Your manuscript is not used to train models.Open Journal of Biological Chemistry guide

Should you submit?

Submit if:

  • the paper is rigorous biochemistry with clear mechanistic contribution
  • you value fast, constructive peer review from field experts
  • the work is strong within biochemistry but doesn't reach Cell/Molecular Cell breadth
  • you want the ASBMB community's flagship journal

Think twice if:

  • the finding has cross-disciplinary significance (Molecular Cell, EMBO Journal, or Nature)
  • the paper is primarily cell biology or genetics without a biochemistry core
  • a specialty journal would give better field-specific visibility

A JBC biochemistry depth check can help assess whether the mechanistic evidence package is strong enough for JBC.

JBC's cited half-life: a different citation window

ASBMB's current metrics page reports a cited half-life of 18.8 years (checked 19 October 2026). Read this alongside the two-year JIF, rather than treating either measure as the journal's definitive quality score.

The half-life describes the age distribution of papers receiving citations. It does not promise that a new paper will be cited for that many years, measure the lifespan of an individual finding, or establish that JBC has the longest-lasting citations in biology.

Measure
Current ASBMB snapshot
How to use it
Two-year JIF
4.1 (2025)
Recent citation context, not a manuscript quality score
Cited half-life
18.8 years
Age of the literature receiving citations
Total citations
277,700 (2025)
Citation volume, not citations per article

For a submission decision, ask whether the journal reaches the researchers who can use and evaluate the contribution. Citation windows can inform that decision, but they cannot replace the scope and evidence checks above.

JBC vs Modern Alternatives: When the Classic Journal Still Wins

JBC competes with journals that didn't exist when it was founded in 1905. Some of those competitors have flashier IFs. But IF isn't the whole picture, and choosing the right journal means thinking about what kind of impact you want your paper to have.

Journal to compare
Question for your manuscript
JBC
Is the central contribution molecular or biochemical insight, or a method or resource that enables it?
Molecular Cell
Does the main claim need a cell-biology audience?
PLOS Biology or Nature Communications
Can you explain why researchers outside the immediate specialty need the finding?
eLife
Does its current review and publication model match your goals and funder's requirements?

When to consider JBC: Your central claim advances molecular or biochemical understanding, or provides an enabling method or resource. Enzyme characterization, protein structure-function studies and metabolic pathway analysis can fit when the contribution is clear. The current scope also leaves room for advances that precede complete mechanistic resolution.

When to compare alternatives: If the strongest contribution is to a different technical community, compare that community's journals using their current scope and article criteria. A higher JIF alone is not a reason to send a paper to readers who cannot assess its main claim.

These are Manusights routing questions, not publisher promises about review outcomes or future citations. Check each candidate's current publication model, access terms and funder compatibility before choosing.

A JBC vs higher-tier journal check can help you figure out whether your paper's biochemistry is strong enough for JBC or whether a different venue fits better.

What Pre-Submission Reviews Reveal About JBC Submissions

For a JBC manuscript, three checks follow from ASBMB's current scope and its emphasis on rigorous design, clear alignment between data and conclusions, transparency and reproducibility.

A contribution whose molecular or biochemical value is unclear. State the conceptual advance, mechanistic foundation, or enabling method or resource. A phenotype or correlation needs a clear contribution to that audience, but incomplete mechanistic resolution is not an automatic exclusion under the expanded scope.

Identify what the study establishes and what remains unresolved. If a mechanistic claim depends on a particular experiment, explain that dependency rather than presenting a correlation as its resolution.

An extension without a clear advance. A new substrate, variant or binding partner needs an explanation of what it changes about the underlying understanding or what new research it enables. Technical correctness alone does not explain the contribution's value.

Compare the finding with the closest prior work and identify the decision or hypothesis it changes. Treat this as an editorial judgment to support with evidence, not a prediction based on an estimated acceptance rate.

Conclusions that outrun the design. Separate a demonstrated effect, a proposed explanation and a remaining test. Check whether the controls and analysis support the strongest conclusion, especially when a cellular or organismal result is used to infer a molecular mechanism.

Make the data and analysis inspectable enough for another researcher to evaluate that boundary. These checks apply ASBMB's published priorities; they are not a documented distribution of JBC rejection reasons.

Frequently asked questions

The Journal of Biological Chemistry (JBC) has a 2025 Journal Impact Factor of 4.1 and a five-year JIF of 4.3. It is ranked Q2 in Biochemistry & Molecular Biology and is the flagship journal of the American Society for Biochemistry and Molecular Biology (ASBMB).

We have not verified a current acceptance rate for Journal of Biological Chemistry. Check Elsevier’s journal catalog for the publisher’s current figure; an unverified figure does not mean the publisher reports none.

Yes. JBC is universally recognized in biochemistry as the field's community journal. Founded in 1905, it publishes rigorous biochemistry broadly and has been fully open access since 2021. A strong JBC paper demonstrates rigorous biochemistry, though it is not a prestige journal like Cell or Nature.

Molecular Cell JIF 16 publishes approximately 200 highly selective papers. JBC's strength is breadth and accessibility; Molecular Cell is for deep mechanistic cell biology with stronger selectivity.

Yes. JBC has been fully open access since 2021. All published articles are freely accessible. The journal is published by the American Society for Biochemistry and Molecular Biology (ASBMB).

JBC is currently Q2 in the JCR Biochemistry & Molecular Biology category, with an IF of 4.1 and a five-year JIF of 4.3. It previously held Q1 status when the IF was higher. The Q2 ranking still places it in the upper half of the field, and the journal's reputation often carries more weight than the quartile alone.

Yes. Despite a lower IF than journals like Molecular Cell or EMBO Journal, JBC remains the ASBMB's flagship journal and is universally recognized in biochemistry.

References

Sources

  1. Clarivate Journal Citation Reports (released June 2026)
  2. JBC author guidelines

Before you upload

Want the full picture on Journal of Biological Chemistry?

Scope, selectivity, what editors want, common rejection reasons, and submission context, all in one place.

These pages attract evaluation intent more than upload-ready intent.

Private API processing. Your manuscript is not used to train models.

Put the guidance to work

Build a journal decision from more than one signal.

Use comparison data as a starting point, then confirm the live source that governs the actual submission decision.

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