Journal Guides8 min readUpdated Apr 1, 2026

Science Advances Acceptance Rate

Science Advances acceptance rate is about 90%. Use it as a selectivity signal, then sanity-check scope, editorial fit, and submission timing.

Research Scientist, Neuroscience & Cell Biology

Author context

Works across neuroscience and cell biology, with direct expertise in preparing manuscripts for PNAS, Nature Neuroscience, Neuron, eLife, and Nature Communications.

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Selectivity context

What Science Advances's acceptance rate means for your manuscript

Acceptance rate is one signal. Desk rejection rate, scope fit, and editorial speed shape the realistic path more than the headline number.

Full journal profile
Acceptance rate~10%Overall selectivity
Impact factor12.5Clarivate JCR
Time to decision1-4 weekFirst decision
Open access APC$5,000Gold OA option

What the number tells you

  • Science Advances accepts roughly ~10% of submissions, but desk rejection accounts for a disproportionate share of early returns.
  • Scope misfit drives most desk rejections, not weak methodology.
  • Papers that reach peer review face a higher bar: novelty and fit with editorial identity.

What the number does not tell you

  • Whether your specific paper type (review, letter, brief communication) faces the same rate as full articles.
  • How fast you will hear back — check time to first decision separately.
  • What open access costs — $5,000 for gold OA.

Quick answer: Science Advances accepts approximately 10% of submissions. The journal receives about 20,000 manuscripts per year and publishes roughly 2,263 articles. About 90% are rejected, most without external review. The median first editorial decision is ~31 days. If you survive past 4-5 weeks without a rejection, you're likely in peer review.

How Science Advances Compares

Journal
Acceptance
IF (2024)
APC
Desk decision
Best for
Science Advances
~10%
12.5
$5,450
~31 days
Physical sciences, earth sciences, interdisciplinary
Nature Communications
~8%
15.7
$7,350
8 days
Biology, biomedical, all sciences
PNAS
~16%
9.1
$4,975
18 days
Social science, environmental, evolutionary biology
eLife
~25%
N/A (delisted)
$3,000
~14 days
Open biology, transparent review
Cell Reports
~14%
6.9
$5,450
4 days
Mechanistic cell/molecular biology
PLOS ONE
~31%
2.6
$2,477
17 days
Technically sound, any field

Science Advances is more selective than most researchers expect. The ~10% acceptance rate puts it in the same tier as Nature Communications, not in the PNAS/eLife range.

The Acceptance Funnel: What Happens to 100 Submissions

Stage
Papers remaining
What happens
Submitted
100
Manuscript enters AAAS system
Technical check
97
3 returned for formatting or completeness
Sent to deputy editor
97
One of 12 DEs (each handling 50-100 papers/month) triages
Desk rejected
-80
~80% rejected without external review
Sent to reviewers
17
DE recruits 2-3 reviewers with expertise spanning the paper's range
Rejected after review
-5
Reviews negative on rigor, significance, or completeness
Revision requested
12
Major or minor revision
Rejected at revision
-2
Revision didn't adequately address concerns
Accepted
10
Published in Science Advances

The desk is the filter. About 80 of every 100 submissions never reach a reviewer. Among the ~17 that do, roughly 60% are eventually accepted, a much friendlier number than the headline ~10%.

Why Desk Rejection Is So High

Science Advances editors are working scientists (not full-time professional editors). Each of the 12 deputy editors handles 50-100 papers per month alongside their own research. They triage fast based on three questions:

1. Is the advance more than incremental? Senior Deputy Editor Warren Warren has said publicly that the most common author mistake is overstatement: "if I need a dictionary to understand some of your adjectives, I will bet you did too." The paper needs to show significance and impact that is more than incremental over existing work.

2. Does this matter beyond one subfield? Science Advances publishes for a cross-disciplinary audience. If only one narrow specialist community would care, a top field journal is the right home.

3. Is the literature comparison honest? Editors check whether you've cited and compared against the most relevant prior work, not just work that makes your paper look better. Missing a directly competing result is a fast desk rejection.

The Timeline: What to Expect

Stage
Duration
Source
Submission to first decision
~31 days (median)
Academic Accelerator
Desk rejection
2-4 weeks typical, up to 50+ days
SciRev author reports
First-round peer review
4-12 weeks
SciRev author reports
Submission to acceptance
~6 months
AAAS editorial data
Acceptance to publication
2-4 weeks
AAAS

The 31-day median first decision includes both desk rejections and reviewed-paper decisions. If you haven't heard anything by week 5, you're likely past the desk, most desk rejections arrive earlier.

What authors actually report (SciRev data):

  • Best case: desk pass in 1-2 weeks, reviews in 4 weeks, acceptance in ~10 weeks
  • Typical: desk decision in 2-4 weeks, reviews in 8-12 weeks, total 5-7 months
  • Worst case: 50+ day desk decision, 6-9 months in review, editor changes mid-process

The wide variance comes from the working-scientist editorial model. Part-time editors have research deadlines, travel schedules, and sabbaticals that create bottlenecks.

What Gets Accepted

Science Advances has carved specific niches where acceptance rates may be slightly higher:

  • Physical sciences and materials: Chemistry, physics, materials, the journal's editorial expertise is deepest here
  • Earth and environmental sciences: Climate, geology, ecology
  • Genuinely interdisciplinary work: AI + materials, genomics + ecology, social science + natural science bridges
  • Longer-format discoveries: Papers needing 6,000+ words and 8+ figures to tell the story convincingly

What consistently fails:

  • Biology-heavy papers (Nature Communications is the natural home)
  • Specialist work dressed up in broad language (editors see through this)
  • Papers from the Science cascade that weren't reframed for Science Advances' audience
  • Methods papers without a clear scientific advance beyond the method itself

The Science Cascade

About 30% of Science Advances papers were originally submitted to Science and transferred after rejection. Transferred papers carry reviewer comments forward, which can accelerate review, but transfer is NOT auto-acceptance. Some transfers are desk-rejected at Science Advances too.

Strategic calculus: If your paper is borderline for Science, submit there first. A Science desk rejection costs 2-4 weeks and gives you a transfer with reviewer comments. But if the paper clearly needs the longer Science Advances format, submit directly.

How to Improve Your Odds

  1. Answer the "so what?" in the first sentence of the abstract. Editors read dozens of papers a day. If the broader significance isn't obvious immediately, the paper gets desk-rejected.
  2. Cite and compare honestly. Missing a directly competing result is one of the fastest paths to desk rejection.
  3. Match the format to the story. If your finding can be told in 3,000 words, it might belong in Science. If it needs 6,000+ words with extensive data, Science Advances is the right venue.
  4. Suggest 5+ reviewers from different disciplines. Science Advances publishes interdisciplinary work, and editors need reviewers spanning the paper's range.
  5. Get a pre-submission read. A Science Advances framing check assesses whether the significance framing hits the cross-disciplinary bar or whether a different journal gives better first-attempt odds.

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What We've Seen Behind the Acceptance Rate Numbers

Having reviewed hundreds of manuscripts targeting Science Advances through our Science Advances submission readiness check, we can add context the published acceptance rate doesn't capture.

The ~10% post-review acceptance rate is the number that matters, but the journey to that 10% starts with a brutal editorial screen. Science Advances processes 400+ new manuscripts per week across roughly 50 deputy editors and 350+ associate editors, all active research scientists. About 90% of submissions are rejected, most without external review. The desk rejection decision can come in 2-9 days when clear-cut, but author-reported data shows some cases stretching to 56-87 days.

The most predictive factor we've identified: whether the abstract can excite a reader outside the immediate subfield. Science Advances editors have openly acknowledged rejecting papers where "the science had real significance, but the editors and reviewers could not see it." The framing problem is fixable before submission. The science problem usually isn't.

One pattern specific to Science Advances: desk rejection appeals are not considered. This is final. If you're desk-rejected, your only option is to submit elsewhere or wait and resubmit with substantial changes. Getting the cross-disciplinary framing right on the first submission isn't optional at this journal.

Submit if / Think twice if

Submit if:

  • the paper presents a finding that is genuinely more than incremental and matters beyond one subfield: the kind of paper that clears Science Advances' editorial screen demonstrates significance the editor can explain to a colleague in a different field without jargon
  • the manuscript needs the longer Science Advances format (6,000+ words, 8+ figures) to tell the story convincingly: papers that require extensive data presentation and cross-disciplinary context fit this journal's format better than short-format alternatives like Physical Review Letters or Nature Communications Briefs
  • the work falls within Science Advances' strongest areas: physical sciences, materials, earth and environmental sciences, or genuinely interdisciplinary research bridging natural science with social or computational methods
  • the cross-disciplinary significance framing is ready at the abstract level: if you can write the first sentence of the abstract for a reader outside your subfield and it still lands, you are past the first editorial screen

Think twice if:

  • the paper is primarily biology or biomedical: Nature Communications is the natural venue for biology-heavy cross-disciplinary work, and Science Advances editors with physical science expertise are less equipped to evaluate and champion it through review
  • the work is incremental within one subfield dressed in broad language: the 12 deputy editors are working scientists who know their fields; framing a specialist advance as broadly significant does not change what the paper actually demonstrates
  • the paper came from a Science cascade rejection and has not been reframed: Science Advances does not accept transfers automatically, and a paper that pitched Science-level significance and failed needs a different narrative, not the same abstract submitted one tier down
  • the editorial timeline variance is a hard constraint for your situation: desk decisions reported up to 50+ days and first decisions stretching to 3-4 months are real, and if you have a defense deadline or grant report window, the timeline risk should factor into journal selection

What Pre-Submission Reviews Reveal About Science Advances Submissions

In our pre-submission review work evaluating manuscripts targeting Science Advances, three patterns generate the most consistent desk rejections. Each reflects the journal's standard: an advance that is genuinely more than incremental, framed for a cross-disciplinary audience, with an honest and complete literature comparison.

Abstract framing written for the subfield, not the cross-disciplinary audience. The failure pattern is a paper with real significance in its domain where the abstract opens with field-specific context that only specialists in that area would recognize as meaningful. Science Advances' 12 deputy editors each handle 50-100 papers per month across disciplines. The editor reading your manuscript may not be in your subfield, and they triage based on whether the broader significance is immediately clear. Senior Deputy Editor Warren Warren has noted publicly that the most common author mistake is overstatement combined with jargon: "if I need a dictionary to understand some of your adjectives, I will bet you did too." The fix is not simplifying the science; it is opening the abstract with the significance in terms a non-specialist can evaluate. During editorial triage, papers that do not demonstrate cross-disciplinary significance in the first two sentences are desk-rejected regardless of the science behind them.

Specialist work with broad language layered on top. The failure pattern is a paper where the actual content is a technical advance within one subfield, with a conclusion section that adds phrases like "with implications for" or "potentially enabling" to claim cross-disciplinary relevance. The editor has read this framing pattern many times. The question is whether the cross-disciplinary significance is demonstrated by the results, not asserted in the discussion. A materials paper whose real contribution is a synthetic yield improvement is not a Science Advances paper because the conclusion mentions potential solar cell applications. The editor asks what a researcher in earth science, social science, or a different physical science subfield would do differently after reading the paper. If the answer is nothing concrete, the paper does not clear the desk.

Science cascade submission not reframed for Science Advances' audience. About 30% of Science Advances papers were originally submitted to Science and transferred after rejection. The failure pattern is treating that transfer as a step down in selectivity rather than a submission to a different journal with a different editorial model. Science evaluates for exceptional significance to the scientific community broadly; Science Advances evaluates for significance beyond one subfield with cross-disciplinary framing. A paper that was desk-rejected at Science because the editorial board disagreed about whether it merited the Science significance bar may still fail at Science Advances if the framing was not adjusted. Transferred papers carry reviewer comments forward, which helps at the peer review stage, but the Science Advances desk review is independent and can desk-reject a transfer. A Science Advances transfer framing check can assess whether the cross-disciplinary framing and abstract meet Science Advances' independent editorial screen, separate from whatever the previous journal evaluated.

What the acceptance rate does not tell you

The acceptance rate for Science Advances does not distinguish between desk rejections and post-review rejections. A paper desk-rejected in 2 weeks and a paper rejected after 4 months of review both count the same. The rate also does not reveal how acceptance varies by article type, geographic origin, or research area within the journal's scope.

Acceptance rates cannot predict your individual odds. A strong paper with clear scope fit, complete data, and solid methodology has substantially better odds than the headline number suggests. A weak paper with methodology gaps will be rejected regardless of the journal's overall rate.

Before submitting, a Science Advances acceptance odds check identifies whether the cross-disciplinary framing puts you in the above-average-odds group or the desk-rejection-at-risk group.

Before you submit

The difference between a Science Advances desk rejection and a paper that enters peer review is almost always the cross-disciplinary framing argument, not the underlying science. Editors decide in 2-9 days and they are screening for significance that travels beyond one subfield. A Science Advances desk-rejection check catches the specific framing gaps before you pay the $5,450 APC and wait for a decision.

Most researchers discover these problems after submission, when the cost is months of review time and a rejection letter. Catching them before submission is the highest-leverage action you can take.

Frequently asked questions

Approximately 10%. Science Advances receives about 20,000 submissions per year and publishes roughly 2,263 articles. About 90% of submissions are rejected, most without external review. This makes it comparable in selectivity to Nature Communications (~8%) though with a different editorial model.

Median time to first editorial decision is about 31 days. Desk rejections typically arrive within 2-4 weeks, though some authors report waits of 50+ days. The working-scientist editorial model means editors are juggling their own research alongside triage.

About 90% of submissions are rejected, most without external review. The 12 deputy editors each handle 50-100 papers per month. The primary desk filter is whether the advance is genuinely more than incremental and relevant beyond one subfield.

Three main patterns: (1) the advance is incremental rather than genuinely surprising, (2) the finding only matters to one narrow subfield, and (3) the literature comparison is unfair or incomplete. Senior Deputy Editor Warren Warren has noted that overstatement in titles and abstracts is the most common author mistake.

Science Advances (~10% acceptance, $5,450 APC, working-scientist editors) is strongest in physical sciences, earth sciences, and interdisciplinary research. Nature Communications (~8% acceptance, $7,350 APC, professional editors) dominates in biology and biomedical sciences. Both are highly selective broad-scope OA journals.

References

Sources

  1. Science Advances journal homepage, AAAS.
  2. Beating the odds for journal acceptance, Warren Warren, Science Advances (2023).
  3. Science Advances reviews on SciRev.
  4. Clarivate Journal Citation Reports (JCR 2024, released June 2025).

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